Focused ultrasound subthalamotomy in Parkinson’s disease: Lesion topography and improvement in cardinal motor features
Objective: To describe the topography of unilateral subthalamic nucleus (STN) lesions performed by magnetic-resonance guided focused ultrasound (MRgFUS) in Parkinson’s disease (PD), and define correlations…Effectiveness of lead position with microelectrode recording based support vector machine for characterizing the sub-cortical-structures via deep brain stimulus in Parkinson`s disease
Objective: To develop artificial intelligence(AI) machine/deep learning techniques for processing/analyzing MER signals of STN which will help the surgical-team (neurologists,neurosurgeons) for deciding optimal location of…Use of a new Stimulation Field Visualization Tool in Parkinson’s Disease Subjects Treated with Subthalamic Nucleus Deep Brain Stimulation (sub-analysis from INTREPID RCT)
Objective: To describe the location of stimulation fields as applied to optimized programming parameters in a cohort of STN DBS PD patients participating in INTREPID…Neural activity in the subthalamic nucleus in association with reward/loss processing in patients with Parkinson’s disease
Objective: To elucidate the electrophysiological correlates of the reward and loss processing during incentive anticipation and feedback in the subthalamic nucleus (STN) of patients with…Intraoperative test objectively for discovering optimal electrode site for effective imaging (by eye) and bilateral STN-DBS stereotactic functional neurosurgery
Objective: To convolve the subject-specific (SS) electric-stimulus-field (ESF) with tremor-progress and progression quantified through accelerometer and stimulus-induced adverse side-effects (SIASE), exhibit visually (by eye) in…A retrospective analysis of multicenter brain signal data recorded in Parkinson’s subjects implanted with deep brain stimulation leads
Objective: To assess the prevalence and factors of detectable local field potential (LFP) signals in the subthalamic nucleus (STN) of Parkinson’s disease (PD) patients. Background:…Objective study of intra operative test for discovering optimal electrode site for effective imaging and bilateral STN-DBS stereotactic functional neurosurgery
Objective: The objective is to examine the microrecording(MER, intra operative) and differentiate stimulus induced micro lesion effect on cardinal motor features of Parkinson's disease. Background:…Quantitative study of T-type Ca2+ channels in the subthalamic nucleus neurons towards Parkinson’s disease
Objective: From the pathophysiological perspectives, Parkinson’s disease (PD) can be viewed as a prototypical disorder of “brain arrhythmias”. Therefore, the modulation of relevant ion channels…Overcoming Stimulation-Related Side Effects And Improving Outcome By Proper Programing Of Subthalamic Stimulation Of Parkinson’s Disease: Cases Report
Objective: We reported three cases of subthalamic deep brain stimulation (STN-DBS) of Parkinson’s disease (PD), with successful management of challenging issues during programing. Background: Proper…Effectiveness of dopaminergic drugs on motor symptoms in Parkinson’s disease patients with deep brain stimulation of subthalamic nucleus
Objective: To compare the effectiveness of dopaminergic drugs on motor symptoms assessed by UPDRS- III in Parkinson’s disease patients pre and post deep brain stimulation…
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