INTREPID Trial: A Prospective, Double blinded, Multi-center Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple-Source, Constant-Current Rechargeable System in Parkinson’s Disease
Objective: The objective of the INTREPID clinical trial is to assess the improvement in motor function and quality of life in patients with advanced, levodopa-responsive…Meta-analysis of mortality following Subthalamic and Pallidal deep brain stimulation for patients with Parkinson’s disease
Objective: The aim of this meta-analysis is to compare mortality after subthalamic (STN) and pallidal (GPi) deep brain stimulation (DBS) for patients with Parkinson's disease…Four year outcomes of a prospective, multi-center trial evaluating Deep Brain Stimulation with a new multiple-source, constant-current rechargeable system in Parkinson’s disease
Objective: To evaluate the four year, long-term follow up results of patients in the VANTAGE clinical study that employed multiple independent current control (MICC) Deep Brain…The battery longevity of implantable pulse generators (IPG) in Parkinson’s disease (PD) is affected by IPG model, number of previous IPG replacements and stimulation energy delivered.
Objective: To determine the effects of stimulation parameters, IPG model and the number of previous IPG replacements on IPG battery longevity. Background: For some patients rechargeable…5-year results from the NSTAPS trial: comparing bilateral deep brain stimulation of the globus pallidus pars interna versus the subthalamic nucleus for advanced Parkinson’s disease.
Objective: Comparing motor, cognitive, and psychiatric outcome 5 years after bilateral deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) and the subthalamic…Somnolence as untoward stimulation effect in subthalamic deep brain stimulation (STN DBS) for Parkinson’s disease (PD)
Objective: Excessive daytime sleepiness is a relatively common feature in PD. However, it has not been reported as a side effect of STN DBS. We…Improvement of memory guided saccade amplitude by the STN DBS and target eccentricity
Objective: To investigate whether the subthalamic nucleus (STN) deep brain stimulation (DBS) improves the memory guided saccade (MGS) amplitude in the same degree in small…Twiddler Syndrome in Deep Brain Stimulation
Objective: Twiddler syndrome is one of the major complications in DBS treatment. Background: The patient intentionally and subconsciously spins internal pulse generator Spinning generally causes…Pathway Selective Deep Brain Stimulation Derived from Patient-Specific Models
Objective: The goal of this work is to quantify the specific pathways directly activated by clinical DBS settings. Background: Deep brain stimulation (DBS) of the…Neuropsychiatric symptoms after bilateral stimulation in Parkinson’s disease: subthalamic nucleus versus globus pallidus internus.
Objective: The aim of this prospective study is to compare the effects of GPi and STN stimulation in PD patients on neuropsychiatric disorders and quality…
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