Can intraoperative clinical testing really predict the effects of deep brain stimulation in the subthalamic nucleus?
Objective: To evaluate whether stimulation-induced therapeutic and side effects of the permanent electrode are predictable by intraoperative test stimulation with clinical examination. Background: Intraoperative test…A new tool to measure the impact of deep brain stimulation on Parkinson’s disease patients: Development and validation of the deep brain stimulation impairment scale (DBS-IS)
Objective: To develop a questionnaire that measures impairments related to deep brain stimulation (DBS). Background: DBS has considerable influence on motor and non-motor symptoms in…Implantable pulse generator (IPG) longevity decreases following each replacement surgery in Parkinson’s disease (PD) patients treated with bilateral sub-thalamic nucleus deep brain stimulation (STN-DBS)
Objective: To investigate the influence of the number of implantable pulse generator (IPG) replacement surgeries and the IPG model on battery life in bilateral STN…The contribution of the subthalamic nucleus in gait initiation of subjects with Parkinson’s disease
Objective: We investigated the contribution of the subthalamic nucleus (STN) in gait initiation of subjects with Parkinson's disease (PD). Background: Gait initiation is the transient…Unilateral subthalamotomy in Parkinson´s disease: Cognitive and neuropsychiatric effects and correlation with lesion size
Objective: To assess cognitive and neuropsychiatric effects of unilateral subthalamotomy in Parkinson´s disease (PD) and their correlation with lesion size. Background: Surgery for treatment of…Chronic directional subthalamic nucleus deep brain stimulation in Parkinson’s disease – A pilot study
Objective: This pilot study aimed to assess the therapeutic potential of chronically implanted directional DBS leads in patients with Parkinson's disease. Background: The therapeutic effect…Improvement of impulse control disorder in Parkinson’s disease patients treated with subthalamic nucleus stimulation
Objective: To find effects of subthalamic deep brain stimulation on impulse control disorder in patients with Parkinson's disease. Background: Parkinson's disease (PD) is a common…Is awake intraoperative mapping still necessary for bilateral subthalamic stimulation for Parkinson’s disease in a modern surgical environment?
Objective: To study the impact of the absence of awake clinical evaluation during subthalamic nucleus (STN) deep brain stimulation (DBS) on parameters of stimulation and…The effect of STN-DBS on movement initiation control is modulated by the noradrenergic system: Evidence of an interaction from a combined pharmacological/DBS/EEG study
Objective: Assessing the role of the noradrenergic system underlying the effect of subthalamic nucleus stimulation (STN-DBS) on akinesia. Background: Slowness in movement initiation, associated with…Clinical outcomes of pallidal and subthalamic nucleus deep brain stimulation in isolated cranial and cranio-cervical dystonia
Objective: To evaluate clinical outcomes of deep brain stimulation (DBS) of globus pallidus internus (GPi) or subthalamic nucleus (STN) for isolated cranial or cranio-cervical dystonia.…
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