Beyond Parkinson´s disease and synucleinopathies: unexpected identification of prodromal corticobasal syndrome by the updated MDS research criteria for prodromal PD
Objective: The aim of the current study was to determine the proportion of patients, initially classified as having prodromal Parkinson’s disease (pPD), phenoconverted to manifest…Understanding Social Isolation before, during and after the Covid-19 pandemic among Patients with Parkinson’s disease
Objective: The aim of this study was to understand and measure the effect of social network support in patients with Parkinson’s disease(PwP) before, during and…Genome-wide association identifies novel etiological insights associated with Parkinson’s Disease in African and African admixed populations
Objective: To provide a genome-wide association study (GWAS)- based insight into the genetics of Parkinson’s disease (PD) in Africans and African admixed populations. Background: Understanding…Transferrin as a possible CSF biomarker in neurodegenerative proteinopathies
Objective: The aim of this study was to determine whether cerebrospinal fluid (CSF) levels of transferrin differ between patients with Parkinson´s disease (PD), multiple system…Exosomal α-synuclein in Multiple system atrophy and parkinson’s disease cause distinct synucleinopathies
Objective: In this study, we investigated the differences in exosomal α-syn between MSA and PD patients. Background: Parkinson's disease (PD) and multiple system atrophy (MSA)…An Analysis of Subgroups of Multiple System Atrophy Patients from Ampreloxetine Phase 3 Trials
Objective: To present results in the subset of patients with multiple system atrophy (MSA) and relevant MSA subgroups from two ampreloxetine phase 3 trials for…Peripheral Synucleinopathy in Essential Tremor Plus Patients with Parkinsonian Features and Normal Dopamine Transporter Imaging
Objective: To describe results of skin biopsy for phosphorylated alpha-synuclein (P-SYN) in patients with essential tremor (ET) with parkinsonism. Background: Patients with longstanding ET may…In vivo proteomic investigation of deeply phenotyped parkinsonian syndromes for biomarkers of differential diagnosis
Objective: To investigate deeply-phenotyped cohorts of parkinsonian syndromes using proteomic technologies for identification of biomarkers for differential diagnosis Background: Proteomic technologies like Olink® Explore 3072…Widespread Synuclein pathology in hyposmics precedes dopamine transporter deficit in PARS
Objective: The Parkinson Associated Risk syndrome (PARS) study is designed to identify a Parkinson disease (PD) biomarker/clinical marker derived cohort enriched to develop typical symptoms…Clinico-pathological correlations in atypical parkinsonism
Objective: We aim to assess diagnostic accuracy of the Parkinson-plus syndromes (PPS) using the current consensus criteria, whilst identifying the diagnostically most salient clinical features.…
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