MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Tics(also see Gilles de la Tourette syndrome): Clinical features"

  • 2025 International Congress

    Efficacy and Safety of Ecopipam for Tourette Syndrome (TS): Results From a Phase 3, Randomized, Double-Blind, Placebo-Controlled Withdrawal Trial

    K. Tomczak, S. Atkinson, D. Kim, M. Miller, P. Rice, G. Karkanias, F. Munschauer, S. Wanaski, T. Cunniff, D. Gilbert (Chicago, USA)

    Objective: To evaluate the efficacy and safety of ecopipam, a dopamine D1 receptor antagonist, as a maintenance therapy in children, adolescents, and adults with TS.…
  • 2025 International Congress

    Sensory sensitivities in individuals with Tics and Tourette Syndrome

    R. Burke, I. Malaty (Gainesville, USA)

    Objective: We aim to review patterns of sensory sensitivity in patients with tics and Tourette's syndrome to gain insight into this under-reported phenomenon. Background: Patients…
  • 2025 International Congress

    STOP-TIC Study: Strengthening Tourette Treatment Options using TMS to Improve CBIT, a randomized sham-controlled trial

    J. Frey, J. Sherman, T. Mcgaughey, J. Suffridge, M. Khan, E. Reid, U. Najib, A. Wagle Shukla, A. Murray, M. Okun, IA. Malaty (Morgantown, USA)

    Objective: To determine if accelerated repetitive transcranial magnetic stimulation (rTMS) administered prior to Comprehensive Behavioral Intervention for Tics (CBIT) will improve tics in Tourette Syndrome…
  • 2025 International Congress

    Aversions as Triggers for Tic Exacerbations

    M. Siegel, P. Graese, I. Malaty (Gainesville, USA)

    Objective: We report three cases of Tourette syndrome wherein aversions were extreme triggers for tics. These mundane sensory stimuli provoked intense tic exacerbation. Background: Tic…
  • 2025 International Congress

    MDS Task Force on Tic Disorders: Development of a New Classification Scheme for Tic Disorders

    I. Malaty, K. Bhatia, K. Black, F. Cardoso, D. Gilbert, M. Hallett, J. Jimenez-Shahed, D. Martino, A. Munchau, M. Okun, P. Pal, J. Piacentini, T. Pringsheim, Y. Worbe, C. Ganos (London, United Kingdom)

    Objective: To establish a clear definition and axis classification scheme for tics that serves to separate phenomenology from etiology. Background: Gilles de la Tourette documented…
  • 2025 International Congress

    Differentiating Functional Tic-like Movements from Organic Tics-Mind the Gap

    A. Cherian, D. Kalikavil Puthanveedu (Thiruvananthapuram, India)

    Objective: This study investigates the clinical characteristics and phenomenological differences between patients with FTM and those with organic tics (OT). Background: Functional tic-like movements (FTM)…
  • 2025 International Congress

    From Subclinical Symptoms to Post-Surgical Challenges: A Pediatric Case of Craniopharyngioma

    M. Gomez Rodriguez, H. Torocsik (Pembroke Pines, USA)

    Objective: To provide a case of subclinical symptoms including motor tics in a child found to have a large craniopharyngioma with post surgical parkinsonism. Background:…
  • 2025 International Congress

    Increased Health Care Utilization in Children/Adolescents With Tourette Syndrome Treated With Dopamine D2 Receptor Antagonists: An Electronic Medical Records Database Analysis

    D. Isaacs, J. Swindle, F. Dabbous, G. Karkanias, S. Atkinson, F. Munschauer, F. Mazhar, C. Pettersson, S. Wanaski, T. Cunniff, K. Tomczak (Nashville, USA)

    Objective: To compare health care resource utilization (HCRU) in dopamine D2 receptor antagonist (D2RA)-exposed versus D2RA non-exposed individuals with Tourette syndrome (TS). Background: TS is…
  • 2025 International Congress

    Determination of the Minimal Clinically Important Difference in the Yale Global Tic Severity Scale Total Tic Score in a Pediatric Population With Tourette Syndrome Receiving Pharmacotherapy

    J. Mcguire, G. Karkanias, R. Bittman, S. Atkinson, F. Munschauer, S. Wanaski, T. Cunniff, D. Gilbert (Baltimore, USA)

    Objective: The aim was to determine the minimal clinically important difference (MCID) on the Yale Global Tic Severity Scale (YGTSS), using the Clinical Global Impression…
  • 2025 International Congress

    Real-World Adverse Event Profile in Children and Adolescents With Tourette Syndrome Treated With Dopamine D2 Receptor Antagonists (D2RAs) Compared With Non-D2RAs

    K. Tomczak, J. Swindle, F. Dabbous, G. Karkanias, S. Atkinson, F. Munschauer, F. Mazhar, C. Pettersson, S. Wanaski, T. Cunniff, D. Isaacs (Bethesda, USA)

    Objective: To further explore the safety profile of dopamine D2 receptor antagonists (D2RAs) for Tourette syndrome (TS) in a community setting. Background: D2RAs (aripiprazole/haloperidol/pimozide) are…
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