Longitudinal shifts in goal-directed and habitual control relate to tic severity and cortico-striatal connectivity in adolescents with Tourette syndrome
Objective: To investigate the balance between goal-directed and habitual control in adolescents with Tourette syndrome (TS) and to determine how longitudinal changes in this balance…From Subclinical Symptoms to Post-Surgical Challenges: A Pediatric Case of Craniopharyngioma
Objective: To provide a case of subclinical symptoms including motor tics in a child found to have a large craniopharyngioma with post surgical parkinsonism. Background:…Increased Health Care Utilization in Children/Adolescents With Tourette Syndrome Treated With Dopamine D2 Receptor Antagonists: An Electronic Medical Records Database Analysis
Objective: To compare health care resource utilization (HCRU) in dopamine D2 receptor antagonist (D2RA)-exposed versus D2RA non-exposed individuals with Tourette syndrome (TS). Background: TS is…Determination of the Minimal Clinically Important Difference in the Yale Global Tic Severity Scale Total Tic Score in a Pediatric Population With Tourette Syndrome Receiving Pharmacotherapy
Objective: The aim was to determine the minimal clinically important difference (MCID) on the Yale Global Tic Severity Scale (YGTSS), using the Clinical Global Impression…Real-World Adverse Event Profile in Children and Adolescents With Tourette Syndrome Treated With Dopamine D2 Receptor Antagonists (D2RAs) Compared With Non-D2RAs
Objective: To further explore the safety profile of dopamine D2 receptor antagonists (D2RAs) for Tourette syndrome (TS) in a community setting. Background: D2RAs (aripiprazole/haloperidol/pimozide) are…Clinical Characteristics and Antipsychotic Medication Use in Pediatric Population Diagnosed With Tourette Syndrome
Objective: To assess the clinical characteristics and rate of antipsychotic medication discontinuation in a pediatric cohort diagnosed with Tourette syndrome (TS). Background: It is estimated…Efficacy and Safety of Ecopipam for Tourette Syndrome (TS): Results From a Phase 3, Randomized, Double-Blind, Placebo-Controlled Withdrawal Trial
Objective: To evaluate the efficacy and safety of ecopipam, a dopamine D1 receptor antagonist, as a maintenance therapy in children, adolescents, and adults with TS.…Sensory sensitivities in individuals with Tics and Tourette Syndrome
Objective: We aim to review patterns of sensory sensitivity in patients with tics and Tourette's syndrome to gain insight into this under-reported phenomenon. Background: Patients…STOP-TIC Study: Strengthening Tourette Treatment Options using TMS to Improve CBIT, a randomized sham-controlled trial
Objective: To determine if accelerated repetitive transcranial magnetic stimulation (rTMS) administered prior to Comprehensive Behavioral Intervention for Tics (CBIT) will improve tics in Tourette Syndrome…Aversions as Triggers for Tic Exacerbations
Objective: We report three cases of Tourette syndrome wherein aversions were extreme triggers for tics. These mundane sensory stimuli provoked intense tic exacerbation. Background: Tic…
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