Towards a Machine Learning Based Classification System for Hyperkinetic Movement Disorders: Generating a Neurophysiological Feature Set
Objective: Generating a set of significant neurophysiological features to build a machine learning based diagnostic system for hyperkinetic movement disorders. Background: Hyperkinetic movement disorders cause…Open-Source Tremor Tracking for MR-guided Focused Ultrasound (MRgFUS): An Objective Approach for Monitoring Treatments
Objective: To describe a novel system developed for real-time noninvasive monitoring of treatment efficacy in patients undergoing MR-guided Focused Ultrasound (MRgFUS) treatment for refractory tremor.…Effect of dopaminergic treatment on digital sensor features in Phase II PASADENA Part 1 in early Parkinson’s disease
Objective: To characterize the sensitivity of smartphone and -watch sensor features to levodopa and dopamine agonist (DA-Tx) treatment. Background: Digital health technology tools (DHTTs) enable…My hands are shaking : A Tunisian cohort study
Objective: Analysis of a cohort of patients diagnosed with tremor concerning the epidemiology, clinical features and etiologies. Background: Tremor is the most common movement disorder…A case of task-specific jaw tremor
Objective: - Background: case report: Isolated task- specific jaw tremor is unusual and has been rarely reported. Herein, we reported a case of task-specific jaw…Automated analysis of pen-on-paper spirals for tremor detection, quantification and differentiation
Objective: To develop and validate an automated analysis algorithm for pen-on-paper Archimedes spirals. Background: Spiral drawings are used in the clinic to identify and quantify…Electrophysiological testing aids the diagnosis of tremor versus myoclonus in clinically challenging patients
Objective: We investigated how clinical electrophysiological testing can help to distinguish tremor versus myoclonus. Background: Tremor is the most common movement disorder and myoclonus its…Novel approach to MDS-UPDRS monitoring in clinical trials: Longitudinal Item Response Theory Models
Objective: Using the unique advantages of Item Response Theory (IRT), we developed unidimensional and multidimensional models to investigate non-tremor and tremor MDS-UPDRS Part 3 changes…Emotional stress exacerbates parkinsonian resting tremor
Objective: To examine the role emotions may play in modulating the characteristics of parkinsonian resting tremor. Background: There is ample evidence showing cognitive stress can…Clinical presentation of Wilson’s disease in pediatric and adult patients: A systematic review
Objective: To identify the most frequent signs and symptoms in Wilson's disease comparing between pediatric and adult patients. Background: Wilson's disease or Progressive Lenticular Degeneration…
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