MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • 2018 International Congress

    Safinamide and Rasagiline effect on motor fluctuation, sleep quality and daytime sleepiness in Parkinson’s Disease: A validated questionnaires study

    C. Liguori, A. Stefani, N. Mercuri, M. Pierantozzi (Rome, Italy)

    Objective: This is an observational study aimed at evaluating the effect of Safinamide and Rasagiline on motor fluctuations, subjective sleep and daytime sleepiness in Parkinson’s…
  • 2018 International Congress

    Safety of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Results from a Phase 3 double-blind, placebo-controlled trial

    R. Pahwa, R. Hauser, M. Worden, P. Bhargava, G. Vakili, A. Agro, D. Blum, W. Olanow, B. Navia (Kansas City, KS, USA)

    Objective: To evaluate the safety of APL-130277 (APL) in the double-blind, placebo-controlled trial Titration Phase (TP) and Maintenance Phase (MP). Background: OFF episodes are a…
  • 2018 International Congress

    Motor and non-motor symptoms of a 7.5-year prospective study of patients with Parkinson’s disease

    A. Yoritaka, Y. Shimo, T. Hatano, N. Hattori (Saitama, Japan)

    Objective: Previously, we retrospectively reported the prevalence and risks of motor and non-motor symptoms of a large number of patients (1453) with Parkinson’s disease (PD)…
  • 2018 International Congress

    Individualization of levodopa treatment using a microtablet dispenser and ambulatory accelerometry

    D. Johansson, A. Ericsson, A. Johansson, A. Medvedev, D. Nyholm, F. Ohlsson, M. Senek, J. Spira, I. Thomas, J. Westin, F. Bergquist (Gothenburg, Sweden)

    Objective: This four-week open-label observational study describes the effect of introducing a microtablet dose dispenser and adjusting doses based on objective free-living motor symptom monitoring…
  • 2018 International Congress

    Evaluation of non motor fluctuations in Parkinson disease by a visual analogue scale in Surgical Candidates

    JPh. Azulay, C. Brefel-Courbon, C. Tranchant, F. Fluchere, A. Eusebio, M. Vaugoyeau, C. Magnaudet, T. Witjas (Marseille, France)

    Objective: In Parkinson disease (PD) despite the high impact of nonmotor symptoms (NMSs) on patient autonomy and quality of life, evaluation of nonmotor fluctuations (NMF)…
  • 2018 International Congress

    Treatment of Levodopa Dose Failure with Subcutaneous Apomorphine Injection

    S. Isaacson (Boca Raton, FL, USA)

    Objective: We evaluated a subset of patients who were enrolled in the AMIMPAKT trial of sc apomorphine injection to treat morning akinesia (see reference) who…
  • 2018 International Congress

    Efficacy of liquid sinemet on non-motor symptoms in Parkinson’s disease

    M. Danoudis, R. Iansek, C. Boon (Cheltenham, Australia)

    Objective: To investigate the short term effect of liquid sinemet on the non-motor symptoms of people with advanced Parkinson’ disease (PD) who experience complex motor…
  • 2018 International Congress

    Magnetic resonance imaging-guided focused ultrasound unilateral pallidotomy for Parkinson’s disease: A report of 2 patients

    H. Ito, T. Taira, S. Fukutake, K. Yamamoto, T. Yamaguchi, T. Kamei (Fujisawa, Japan)

    Objective: To present two patients of Parkinson’s disease (PD) with Magnetic resonance imaging-guided focused ultrasound (MRgFUS) unilateral pallidotomy. Background: MRgFUS is a new technology that…
  • 2018 International Congress

    Pilot study of a new tool to optimize dopaminergic treatment in Parkinson’s disease: The OPTIPARK Scale Project

    J. Máñez Miró, F. Vivancos-Matellano, P. Martínez-Martín (Mostoles, Spain)

    Objective: Our objective was to develop and pilot test a scale (OPTIPARK) for assessing a patient´s dopaminergic state, allowing the clinician to consider the adjustment…
  • 2018 International Congress

    West Sweden Parkinson Objective Measurement Registry Study (WestPORTS)

    F. Bergquist, A. Ax, A. Sjostrom, S. Wallerstedt (Gothenburg, Sweden)

    Objective: To study a population representative Parkinson’s Disease (PD) patient cohort characterized with objective 6x24h home measurements using the Parkinson Kinetigraph (PKG, Global Kinetics). To…
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