Motor effects and safety of IPX203, an investigational extended-release formulation of carbidopa-levodopa, in advanced Parkinson’s disease: A single-dose study
Objective: Evaluate the efficacy and safety of IPX203 vs. immediate-release (IR) carbidopa-levodopa (CD-LD) and vs. extended-release (ER) CD-LD (IPX066, RYTARY®) in patients with advanced Parkinson’s…Impact and communication of OFF periods in Parkinson disease
Objective: To review existing literature on the impact and communication of OFF periods for patients with Parkinson disease (PwP) and carepartners. Background: Studies show associations…Post-hoc analyses of the recommended starting dose for Rytary based on “off” time
Objective: To determine whether correcting for “off” time duration improves the selection of the final LD dose when converting to extended-release carbidopa-levodopa capsules (ER CD-LD,…The Personal Kinetigraph Fluctuator Score Identifies Motor Fluctuations in Parkinson’s disease
Objective: To evaluate the Personal Kinetigraph (PKG) fluctuator score (FS) in detecting motor fluctuations in Parkinson's disease (PD) patients. Background: Fluctuations of response to levodopa,…Clinical feasibility of a wearable, conformable, sensor patch to monitor motor symptoms in Parkinson’s disease
Objective: 2-part pilot study to evaluate feasibility of a wearable sensor, the prototype NIMBLE system sensor patch, to assess motor symptoms in Parkinson’s disease (PD) patients.…Evaluating the Clinical Efficacy of the Personal KinetiGraph Movement Recording System
Objective: To examine the clinical efficacy of the Personal KinetiGraph (PKG) movement recording in identifying patients with Parkinson’s disease (PD) requiring treatment for motor symptoms.…Improved Detection of Gait Abnormalities in Parkinson’s disease using an IMU Sensor-based System
Objective: To develop an automated system that uses a limited set of IMU sensors to improve the detection of gait abnormalities in Parkinson’s disease during…Personal KinetiGraph (PKG) for Parkinson’s Disease: Experience at a Tertiary Care Center
Objective: To assess objective measurements by Personal KinetiGraph (PKG) in Parkinson’s disease (PD) patients and compare them to self-reported symptoms. Background: Personal Kinetigraph (PKG)…Diphasic Dyskinesias during levodopa-carbidopa intestinal gel (LCIG) infusion: diagnosis and management in clinical practice.
Objective: To describe the occurrence, diagnostic approach, clinical management and outcome of diphasic dyskinesias (Dyskinesias-Improvement-Dyskinesias, DID) in a large group of Parkinson’s Disaese (PD) patients…Clinical Experience with Initiation of Carbidopa/Levodopa Enteral Suspension in Parkinson’s Disease Patients with Cognitive Impairment
Objective: To assess the safety and efficacy of carbidopa/levodopa enteral suspension (CLES) in Parkinson’s disease (PD) patients with cognitive impairment. Background: As Parkinson’s Disease progresses,…
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