MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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    2024 International Congress
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    PPMI
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  • 2024 International Congress

    Baseline NSD-ISS stage predicts long term progression and survival in sporadic PD: 10-year PPMI data analysis

    P. Gonzalez-Latapi, C. Gochanour, H. Cho, S. Ho Choi, C. Caspell, C. Coffey, M. Brumm, Y. Xiao, DE. Lafontant, C. Venuto, C. Tanner, K. Kieburtz, L. Chahine, A. Siderowf, K. Marek, T. Simuni (Chicago, USA)

    Objective: To analyze long term progression in Neuronal Synuclein Disease (NSD) participants who were originally enrolled in the sporadic Parkinson Disease (sPD) cohort in PPMI…
  • 2024 International Congress

    Concordance of Neuropathologic Diagnosis of Lewy Body Disease with Baseline Alpha-Synuclein Seed Amplification Assay in PPMI

    K. Poston, J. Ha, T. Montine, S. Bukhari, T. Foroud, L. Heathers, K. Nudelman, I. Aldecoa, A. Garrido, J. Franz, C. Stadelmann, J-P. Vonsattel, A. Siderowf, L. Chahine, T. Simuni, K. Marek (Stanford, USA)

    Objective: To determine whether the alpha-synuclein seed amplification assay (aSyn-SAA) performed on cerebral spinal fluid (CSF) collected at the baseline (BL) PPMI visit is concordant…
  • 2024 International Congress

    Predictive Accuracy of Baseline DaT-SPECT for Freezing of Gait at 5, 7, and 10-year Follow up in The PPMI Cohort

    J. Li, R. Rajmohan, J. Ruiz Tejeda, N. Phielipp (Irvine, USA)

    Objective: To see if segmentation models of baseline DaT-SPECT striatal binding ratios (SBR) will predict freezing of gait (FoG) in Parkinson’s Disease over a 5,…
  • 2024 International Congress

    The Contribution of APOE4 Genotype on Structural MRI in Parkinson’s Disease: A Study from the PPMI Cohort

    A. Rosal, A. Strafella, S. Martin (Toronto, Canada)

    Objective: To assess the contribution of Apolipoprotein E4 (APOE4) in Parkinson’s Disease (PD)-related cognitive impairment by analyzing its impact on Gray Matter Volume (GMV). Background:…
  • 2024 International Congress

    Assessing the Predictive Accuracy of Baseline Neuropsychiatric and Axial Motor Features for Freezing of Gait in Parkinson’s Disease at 5-year Follow up: The PPMI Cohort

    J. Li, R. Rajmohan, J. Ruiz Tejeda, N. Phielipp (Irvine, USA)

    Objective: To determine if neuropsychiatric and axial motor symptoms at baseline would be predictive of freezing of gait (FoG) at 5-year follow up in participants…
  • 2024 International Congress

    Baseline and Longitudinal NSD-ISS Staging of the PPMI Cohort

    M. Brumm, T. Simuni, C. Gochanour, L. Chahine, K. Poston, S. Chowdhury, C. Coffey, T. Dam, P. Dibiaso, T. Foroud, M. Fraiser, K. Kieburtz, C. Kopil, K. Merchant, B. Mollenhauer, G. Pagano, J. Seibyl, T. Sherer, D. Stephenson, C. Tanner, E. Tolosa, D. Weintraub, Y. Xiao, A. Siderowf, B. Dunn, K. Marek (Iowa City, USA)

    Objective: To apply biological definition and Neuronal α-Synuclein Disease Integrated Staging System (NSD-ISS) to the PPMI baseline and longitudinal dataset. Background: The NSD-ISS Working Group…
  • 2024 International Congress

    Clinical and Neuroimaging Biomarker Predictors of Autonomic Dysfunction in Parkinson’s Disease: A Study Using PPMI Data

    A. Oliveira Franco, M. Machado Schlindwein, J. Rossi Catao, D. Teixeira-Dos-Santos, A. Bieger, T. Hugentobler Schlickmann, L. Angi Souza, C. Mattjie, F. Suzuki, G. Magalhães Pereira, L. Silveira Kupssinskü, L. Vinícius Moura, R. Ravazio, S. Duarte Pinto, M. de Bastiani, R. Barros, E. Zimmer, A. Schumacher Schuh (Porto Alegre, Brazil)

    Objective: To evaluate whether clinical and neuroimaging baseline markers predict the onset of significant dysautonomia over five years in individuals with idiopathic, de novo Parkinson's…
  • 2024 International Congress

    Research Information Disclosure In The PPMI Study: Development Of A Disclosure Process

    T. Tropea, J. Schulze, C. Destro, L. Heathers, B. Henry, JM. Talarico, C. Stanley, M. Mcguire Kuhl, E. Flagg, T. Foroud (Philadelphia, USA)

    Objective: The Parkinson Progression Markers Initiative (PPMI) is a multinational, longitudinal observational study that collects clinical, imaging, biologic, and genetic data from participants with or…
  • 2024 International Congress

    Creation and Performance of a Cognitive Summary Score in de novo Parkinson’s Disease: Results from the PPMI Study

    M. Brumm, R. Kurth, M. York, D. Weintraub ()

    Objective: To determine if a cognitive summary score (CSS) is sensitive in detecting early cognitive deficits in de novo Parkinson’s disease (PD). Background: Cognitive impairment…
  • 2024 International Congress

    Lower plasma piperine levels in Parkinson’s disease: a PPMI metabolomics analysis

    N. Xia, J. Ripping, R. Bakshi, E. Macklin, S. Molsberry, X. Chen, A. Ascherio, M. Schwarzschild (Charlestown, USA)

    Objective: To explore piperine as a potential biomarker for Parkinson’s disease (PD) among GBA and LRRK2 mutation carriers and non-carriers. Background: Piperine is a yellow…
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