Research Information Disclosure In The PPMI Study: Development Of A Disclosure Process
Objective: The Parkinson Progression Markers Initiative (PPMI) is a multinational, longitudinal observational study that collects clinical, imaging, biologic, and genetic data from participants with or…Creation and Performance of a Cognitive Summary Score in de novo Parkinson’s Disease: Results from the PPMI Study
Objective: To determine if a cognitive summary score (CSS) is sensitive in detecting early cognitive deficits in de novo Parkinson’s disease (PD). Background: Cognitive impairment…Lower plasma piperine levels in Parkinson’s disease: a PPMI metabolomics analysis
Objective: To explore piperine as a potential biomarker for Parkinson’s disease (PD) among GBA and LRRK2 mutation carriers and non-carriers. Background: Piperine is a yellow…Clinical and Neuroimaging Biomarker Predictors of Cognitive Dysfunction In Parkinson’s Disease: A Study Using PPMI Data
Objective: This study evaluates whether clinical, biological, and neuroimaging baseline markers can predict the onset of significant cognitive-based milestones developed in these cohorts over a…Parkinson’s Progression Markers Initiative (PPMI): Investigating Biomarker Driven PD Progression
Objective: PPMI is a longitudinal, observational study enrolling PD participants, individuals at risk for PD, and healthy controls (HCs). The study investigates clinical, imaging, genetic…Use of Machine Learning for Identification of Parkinson’s Disease and Mild Cognitive Impairment through Neuroimaging and Biofluid Biomarkers: A Study from the PPMI Cohort
Objective: Since current diagnostic tests for Parkinson’s Disease (PD) and mild cognitive impairment (MCI) focus on individual biomarkers, misdiagnoses can be frequent. This research aims…Characterizing Dopaminergic Correlates of Depression in Parkinson’s Disease: The PPMI Cohort
Objective: We explored the association between cerebrospinal fluid (CSF) dopamine metabolites and transporter denervation in the development of depression in Parkinson Disease (PD). Background: Depression…Characterization of a Novel alpha-synuclein PET radiotracer, [18F]C05-05, in a PPMI Sub-study
Objective: Characterization of the PET radiotracer, [18F]C05-05, in the PPMI Study Background: Validation of imaging biomarkers in Parkinson disease (PD) is a major objective of…Assessing the Accuracy of Clinical features, CSF Dopamine Metabolites, and Striatal Binding Ratios for the Likelihood of Depression Over 10-year Follow Up in the PPMI Cohort.
Objective: To identify whether MDS-UPDRS scores, Dopamine Transporter (DaT) Striatal Binding Ratios (SBRs), or dopamine metabolites cerebrospinal fluid (CSF) concentrations could predict the likelihood of…Creating myPPMI: an Online Portal to Deliver Study Participant Content
Objective: Building a centralized platform to collect patient reported outcomes and provide educational and informational content to participants Background: Patient portals are a valued healthcare…
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2024 International Congress -
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PPMI