MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

MENU 
  • Home
  • Meetings Archive
    • 2024 International Congress
    • 2023 International Congress
    • 2022 International Congress
    • MDS Virtual Congress 2021
    • MDS Virtual Congress 2020
    • 2019 International Congress
    • 2018 International Congress
    • 2017 International Congress
    • 2016 International Congress
  • Keyword Index
  • Resources
  • Advanced Search

A new tool to measure the impact of deep brain stimulation on Parkinson’s disease patients: Development and validation of the deep brain stimulation impairment scale (DBS-IS)

F. Maier, C.J. Lewis, A.A. Kühn, H. Krug, J. Volkmann, A.D. Kirsch, L. Wojtecki, A. Schnitzler, G. Deuschl, J.K. Krauss, C. Woopen, L. Timmermann (Cologne, Germany)

Meeting: 2016 International Congress

Abstract Number: 45

Keywords: Apathy, Non-motor Scales, Scales, Subthalamic nucleus(SIN)

Session Information

Date: Monday, June 20, 2016

Session Title: Surgical Therapy

Session Time: 12:30pm-2:00pm

Objective: To develop a questionnaire that measures impairments related to deep brain stimulation (DBS).

Background: DBS has considerable influence on motor and non-motor symptoms in Parkinson’s disease (PD). While improvements in motor functioning can be easily assessed with general quality of life questionnaires, the measurement of specific DBS non-motor changes often remains insufficient.

Methods: The developmental process of the DBS Impairment Scale (DBS-IS) consisted of four major steps. In the first step, 60 semi-structured interviews three months and one year after DBS-surgery were performed to create 76 items that relate to motor and non-motor functioning in PD patients with DBS. In the second step pilot-testing lead to a rewording of the questions for better understanding. In the third step, a first multicentre survey was performed and 215 patients completed the questionnaire. Thereafter, the items were reduced applying exploratory factor analysis.

Results: The resulting six factors comprised 22 items. These factors were 1. postural instability and gait difficulties (5 items), 2. cognitive impairment (5 items), 3. speaking problems (3 items), 4. apathy (3 items), 5. impulsivity (3 items), and 6. difficulties related to the DBS device (3 items). In the final step, a second multicentre survey was conducted and 391 patients completed the scale. Concerning reliability, all subscales showed high internal consistency (Cronbach’s alpha 0.71-0.90). Finally, construct validity was determined examining the association between the DBS-IS subscales and standard questionnaires e.g. the Parkinson’s disease questionnaire-39 and neuropsychiatric instruments. Construct validity proved high (r>.60, p<.001) with large effect sizes.

Conclusions: With this new outcome parameter, DBS-specific problems can be adequately measured, comparisons between patients are possible, therapy can be adjusted and potential therapeutic outcomes predicted.

The abstract was previously presented at the yearly congress of the German Neurological Society in Duesseldorf in 2015.

To cite this abstract in AMA style:

F. Maier, C.J. Lewis, A.A. Kühn, H. Krug, J. Volkmann, A.D. Kirsch, L. Wojtecki, A. Schnitzler, G. Deuschl, J.K. Krauss, C. Woopen, L. Timmermann. A new tool to measure the impact of deep brain stimulation on Parkinson’s disease patients: Development and validation of the deep brain stimulation impairment scale (DBS-IS) [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/a-new-tool-to-measure-the-impact-of-deep-brain-stimulation-on-parkinsons-disease-patients-development-and-validation-of-the-deep-brain-stimulation-impairment-scale-dbs-is/. Accessed July 15, 2025.
  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

« Back to 2016 International Congress

MDS Abstracts - https://www.mdsabstracts.org/abstract/a-new-tool-to-measure-the-impact-of-deep-brain-stimulation-on-parkinsons-disease-patients-development-and-validation-of-the-deep-brain-stimulation-impairment-scale-dbs-is/

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • What is the appropriate sleep position for Parkinson's disease patients with orthostatic hypotension in the morning?
  • Covid vaccine induced parkinsonism and cognitive dysfunction
  • Life expectancy with and without Parkinson’s disease in the general population
  • An atypical and interesting feature of Parkinson´s disease
  • Screening and Treatment of Depression in Parkinson’s Disease within Movement Disorders Centers: A Quality Improvement Initiative
  • Covid vaccine induced parkinsonism and cognitive dysfunction
  • #25676 (not found)
  • Crack Dancing: An Uncommon Drug-Induced Chorea
  • #24376 (not found)
  • An atypical and interesting feature of Parkinson´s disease
  • A Case of Pregabalin induced Parkinsonism
  • A survey-based analysis of abnormal movements in patients with Postural Tachycardia Syndrome (PoTS)
  • Help & Support
  • About Us
  • Cookies & Privacy
  • Wiley Job Network
  • Terms & Conditions
  • Advertisers & Agents
Copyright © 2025 International Parkinson and Movement Disorder Society. All Rights Reserved.
Wiley