Date: Thursday, June 23, 2016
Session Time: 12:00pm-1:30pm
Location: Exhibit Hall located in Hall B, Level 2
Objective: To identify the body position during sleep in PD patients in comparison to their spouses by using multisite wearable inertial sensors.
Background: Nocturnal hypokinesia represents one of the most distressing nocturnal symptoms in PD,which may lead to patients and caregivers’ burden.Our recent study utilizing wearable sensors indicated that PD patients made fewer,smaller turns in bed in comparison to their spouses, implying the presence of nocturnal axial rigidity(1).The identification of body position during sleep could be clinically important since the presence of akinesia in one static position may be associated with sleep disordered breathing with potential serious complications and fatality(2).
Methods: 18 PD patient pairs were included in the study.All subjects wore 3-axis inertial sensors comprising of accelerometers and gyroscopes over the sternum, bilateral wrists, and ankles(1).They also completed the NADCS and UPDRS.The recording was for 1 night, with the video monitoring in their home.Supine position was identified by the presence of 0 degree of x and y axis and 90 degree of z axis.
Results: 18 PD patients (64.9 +/-7.6yrs),18 spouses 63.8 +/-8.5yrs)completed the study.There were no significant demographic differences between the two groups and demographic data PD patients were shown in Table 1
|Age||64.9 + 7.6|
|Age at onset||55.0 (10.01)|
|Duration of disease||10.0 (5.38)|
|Hoehn&Yahr stage||2.53 (0.44)|
|UPDRS I/II/III/IV||2.22 (1.73) /11.72 (4.82) /22.94 (8.31) /3.33 (2.85)|
|Presence of nocturnal akinesia||60%|
|Total LED (mg)||953.06 (451.89)|
|Night time LED (mg)||68.89 (48.46)|
|Nocturnal akinesia score||1.7 (1.2)|
|Nocturnal dystonia score||0.6 (0.7)|
|Nocturnal cramp score||0.8 (1.0)|
|Total NADCS||3.1 (2.3)|
|Body position (min)||Patients||Spouses||P-value|
|Prone position||0.687 (2.45)||18.582 (31.67)||0.030*|
|Right lateral position||72.368 (69.12)||137.564 (105.39)||0.079|
|Left lateral position||57.383 (109.94)||112.277 (99.53)||0.116|
|Supine position||316.583 (133.17)||209.386 (108.64)||0.034*|
|Upright position||49.702 (44.64)||37.804 (29.94)||0.244|
|Total sleep time||496.722 (81.82)||515.611 (111.69)||0.546|
|Sleep time exclude upright position||447.020 (59.94)||477.808 (116.16)||0.271|
Conclusions: Our study provided the objective evidence that PD patients spent most time of the night in the supine position more than their spouses.This prolonged supine position is likely to be a consequence of their nocturnal hypokinesia.The prolonged supine position in patients with PD may be a critical setting that lead certain patients for nighttime breathing or complications.
To cite this abstract in AMA style:J. Sringean, P. Taechalertpaisarn, C. Thanawattano, R. Bhidayasiri. Body position during sleep in patients with Parkinson’s disease (PD): A sensor-based analysis [abstract]. Mov Disord. 2016; 31 (suppl 2). https://www.mdsabstracts.org/abstract/body-position-during-sleep-in-patients-with-parkinsons-disease-pd-a-sensor-based-analysis/. Accessed December 5, 2023.
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