Session Information
Date: Sunday, October 7, 2018
Session Title: Parkinsonism, MSA, PSP (Secondary and Parkinsonism-Plus)
Session Time: 1:45pm-3:15pm
Location: Hall 3FG
Objective: to Study the profile of akinetic rigid syndromes with special reference to Vascular Parkinsonism
Background: Parkinson disease (PD) is a primary neurodegenerative disease but can also result from a variety of vascular disorders, vascular parkinsonism (VP). Very few studies had characterized disease spectrum of VP.
Methods: This was hospital-based prospective observational study to determine the disease spectrum of VP. All consecutive new patients with akinetic disorders seen between July 2016 and December 2017 were the study cohort. The data collected included: demographic data, vascular risk factors, neurological history and findings, non-motor symptoms, neuroimage features, Hoehn & Yahr staging, and UPDRS score. Vascular Parkinsonism rating scale proposed by Winikates and Jankovic was used for the diagnosis of VP, patients scoring >2 were diagnosed as VP. Clinical syndromes associated with VP were done as proposed by Jellinger.
Results: During the study period 150 patients with akinetic disorder were seen: Pd (81); PD-plus (36); secondary parkinsonism including VP (33). VP accounted for 21[mean age 73.5+6 y; M:F 95:5] (14%). Among VP the distribution of clinical syndromes: VP-lower body type (9); VP indistinguishable from PD (5); VP associated with multi-infarct state (4); and PSP like syndrome (3). Differences in clinical features between VP vs. PD include: male predominance (p=0.01); more elderly (p=0.0006); postural instability (0.001), bladder disturbance (0.0001); and dementia (0.0001). Festinating gait, hyposmia and constipation were more common in PD. Response to levadopa during the short follow-up period was suboptimal.
Conclusions: The prevalence of VP in this study is high when compared to the other studies. There were definite distinguishing clinical features between VP and PD.
References: Jellinger KA. Vascular parkinsonism. 2008;5:237–55.
To cite this abstract in AMA style:
J. Kuragala, J. Murthy, N. Chaudhary, s. Sharma, S. Jaiswal, Y. Reddy. Clinical spectrum of vascular Parkinsonism: A hospital-based study in south India [abstract]. Mov Disord. 2018; 33 (suppl 2). https://www.mdsabstracts.org/abstract/clinical-spectrum-of-vascular-parkinsonism-a-hospital-based-study-in-south-india/. Accessed June 15, 2025.« Back to 2018 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/clinical-spectrum-of-vascular-parkinsonism-a-hospital-based-study-in-south-india/