Session Time: 1:45pm-3:15pm
Location: Agora 3 West, Level 3
Objective: To study vertical oculomotor reflexes(VOR) and the state of the functional system “eyelid” in patients with Parkinson’s disease.
Background: Parkinson’s disease (PD) is a common disorder of middle-aged and elderly people, in which there is degeneration of the extrapyramidal motor system. In some patients, the disease is associated with a range of visual signs and symptoms, including defects in visual acuity, colour vision, the blink reflex, pupil reactivity, saccadic and smooth pursuit movements and visual evoked potentials.
Method: The study involved 250 patients aged 35-70 years. Eye and eyelid movements were evaluated with clinical examination, as well as during video-static histography on the hardware complex “Interacoustics”.
Results: The study showed that the speed characteristics of oculomotor reactions in all the tests used are slowing down, the latency time is increased and the accuracy of saccades is reduced in performing the saccadic test, the rate of smooth tracking and the speed of the slow phase of the OKN decrease, and these violations in the vertical plane are manifested to a greater extent, than in the horizontal. There is a direct correlation between the severity of disorders of oculomotor dysfunction and the severity of the disease, regardless of its duration. A characteristic feature of all PD patients is violation suppression of vertical nystagmus in both directions by fixing the gaze on a moving object with the head already in the early stages of the disease.
Conclusion: Thus, in patients with PD, violations of the vertical vision system are one of the symptoms of this disease. Registration and quantitative analysis of the parameters of the main oculomotor reflexes will allow to evaluate the adequacy of the prescribed therapy, as well as to solve some expert questions.
References: 1. Bodis-Wollner I, Marx MS, Mitra S, Bobak P, Mylin L, Yahr M. Visual dysfunction in Parkinson’s disease. Loss in spatiotemporal contrast sensitivity. Brain 1987; 110 (Pt 6): 1675–98. 2. Bodis-Wollner I, Miri S, Glazman S. Venturing into the no-man’s land of the retina in Parkinson’s disease. Mov Disord 2014b; 29: 15–22.
To cite this abstract in AMA style:M. Salokhiddinov, D. Akramova. Evaluation of Clinical Peculiarities of Violations of Vertical Vision in Patients with Parkinson’s Disease [abstract]. Mov Disord. 2019; 34 (suppl 2). https://www.mdsabstracts.org/abstract/evaluation-of-clinical-peculiarities-of-violations-of-vertical-vision-in-patients-with-parkinsons-disease/. Accessed December 7, 2023.
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MDS Abstracts - https://www.mdsabstracts.org/abstract/evaluation-of-clinical-peculiarities-of-violations-of-vertical-vision-in-patients-with-parkinsons-disease/