PBT434 prevents the accumulation of glial cell inclusions and insoluble alpha-synuclein in a mouse model of Multiple System Atrophy
Objective: To evaluate PBT434 in a transgenic mouse model of multiple system atrophy (MSA) Background: PBT434 is a novel quinazolinone inhibitor of iron-mediated protein accumulation…Cerebrospinal fluid levels of cytokines in multiple system atrophy: A cross-sectional study of the atalan msa registry (CMSAR)
Objective: To compare the cerebrospinal fluid (CSF) levels of 38 cytokines in multiple system atrophy (MSA) patients vs. control and Parkinson’s disease (PD) subjects. Background:…The Catalonian Multiple System Atrophy Registry (CMSAR): The motor features and their impact on disability status in MSA patients
Objective: To assess motor symptoms and their demographic correlates in MSA patients included in the CMSAR as well their impact on daily living activities. Background:…Corticobasal Syndrome: A Single Center Case Series
Objective: To evaluate clinical features of corticobasal syndrome in a tertiary care setting. Background: None. Methods: A retrospective chart review was done. All patients diagnosed…What activities increase the risk of falling in atypical parkinsonian syndromes? A comparative study with Parkinson’s disease
Objective: To determine balance confidence (FoF) in patients with PD and APS by utilizing the 16-items Activities-Specific Balance Confidence Scale (ABC-16), and identify specific activities…Assessment of CSF biomarkers clinical value in Progressive Supranuclear Palsy
Objective: To evaluate diagnostic and prognostic usefulness of a panel of CSF biomarkers in PSP patients presenting with Richardson’s Syndrome (RS). Background: PSP is a…Midbrain Diameter Measurements on High-Resolution Computer Tomography Scans to aid diagnosis of Progressive Supranuclear Palsy
Objective: To establish whether high-resolution computer tomography (CT) scans can aid the diagnosis of progressive supranuclear palsy (PSP), and multiple system atrophy (MSA). Background: The…Peripheral immune activation was associated with multiple system atrophy
Objective: Our aim is to clarify the correlations between peripheral immune activation and the prevalence as well as the disease severity of MSA. Background: Alpha-synuclein…Disease progression and survival of multiple system atrophy: A prospective French cohort study
Objective: We report the first prospective natural history study of MSA combining progression of the disease and mortality. Background: Multiple system atrophy (MSA) is a…The clinical spectrum of motor stereotypies in progressive supranuclear palsy: An early, frequent and underestimated symptom
Objective: To describe the frequency, phenomenology, and clinical and neuropsychological correlates of stereotypies in PSP. Background: Stereotypies are repetitive, patterned and predictable purposeless movements. Unlike…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.