Effect of deep brain stimulation on clinical outcome in Parkinson’s disease patients with different genetic status
Objective: The aim of this study was to evaluate the effect of the genetic status on the clinical outcome of PD patients undergoing DBS. Background:…Clinical phenotype analysis of Parkinson’s disease associated with LRRK2 variants in Chinese Han population
Objective: Our study aimed to compare motor and non-motor symptoms, imaging features and molecular markers of patients with Parkinson’s disease (PD) who are carriers of…FDG-PET and metabolomics in PD-associated GBA variants
Objective: To assess the clinical, cognitive, metabolic, and imaging phenotypes of PD patients carrying the variants p.E365K and p.T408M in the GBA gene (NM_000157.3). Background:…A Theranostic Approach to Intervene the Link Between Parkinson’s Disease (PD) and LRRK – 2 Mutation
Objective: The current research work encircles the main perspective of screening patients for PD with LRRK-2 mutations in patients pertaining to regions in and around…α-Synuclein induced dopaminergic neurons mitochondrial dysfunction via cytochrome c oxidase subunit 2
Objective: To investigate the mechanism of how α-Syn injure the the dopaminergic neurons. Background: The misfolded α-Synuclein(α-Syn) transferring from cells to cells as prion protein…Kufor-Rakeb Syndrome with prominent dystonia and new mutations in ATP13A2 gene in two siblings
Objective: To describe new genetic mutations and unusual clinical findings in two siblings with Kufor Rakeb syndrome, an autosomal recessive etiology of parkinsonism. Background: Kufor-Rakeb…Early synaptic loss and synaptic instability in a mouse model of prodromal Parkinson’s disease
Objective: In order to elucidate very early pathologis of Parkinson’s disease (PD), we focused on synaptic pathologies in a newly developed mouse model of prodromal…Evaluation of the relationship between Leucine-rich repeat kinase 2 (LRRK2) S1647T variants and smoking with risk of Parkinson’s Disease in the Singapore population
Objective: To investigate whether cigarette smoking influences the relationship between S1647T variants and risk of PD in the Singapore population. Background: Case-control studies in southern…Interaction between MAPT H1 and APOE4 in early Parkinson’s Disease
Objective: To define if the high risk MAPT allele of rs393152 (H1 haplotype) is associated with differences in brain structure, clinical presentation, progression or cognitive…Balance and gait analysis of GBA mutation carriers with Parkinson’s disease (PD)
Objective: To use quantitative inertial sensor-based postural sway and gait analysis to determine potential differences in the pattern of balance and gait impairment in the…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.