Deep brain stimulation (DBS) for dyskinetic cerebral palsy: A pilot study
Objective: To investigate whether deep brain stimulation (DBS) is effective in reducing symptoms and improving function in dyskinetic cerebral palsy (CP). Background: DBS targeting the…Clinical study on the correlation between Parkinson’s somatosensory evoked potentials and STN-DBS parameters
Objective: Indications for STN-DBS are assessed based on the clinical symptoms. Our test was a clinical study on the correlation between amplitude and latency of…Zonisamide improves parkinsonism in DLB patients: A randomized phase 3 trial
Objective: To verify the efficacy and safety of zonisamide (ZNS) for parkinsonism in patients with dementia with Lewy bodies (DLB). Background: DLB parkinsonism is responsive…Linking neuroplastic effects to behavioral changes after balance training in Parkinson’s disease: a study protocol of a randomized controlled trial
Objective: In this randomized controlled trial, we will determine the effects of a highly challenging balance training (the HiBalance program) on balance, gait, cognition and…Botulinum toxin in Essential Hand Tremor – A Randomized Double-Blind Placebo-Controlled study with Customized Injection Approach
Objective: To evaluate the safety and efficacy of incobotulinumtoxinA (IncoA) injection for treatment of Essential Tremor (ET). Background: In essential tremor and Parkinson's Disease tremor,…Therapeutic exposures of CX-8998, a potent, selective and state dependent Cav3 channel antagonist in development for Essential Tremor and Parkinson’s disease Tremor in Cav3 driven neurological models
Objective: In this study, we utilized preclinical data to establish predicted human therapeutic exposures of the potent, selective and state-dependent Cav3 channel antagonist, CX-8998, currently…A Preliminary Study of Cinnamomum verum on Anxiety, Locomotor Activity and Emotionality Behaviour in Wistar Albino Rats
Objective: Introduction: Cinnamomum verum is a very common traditional Indian Spice known as Darchini. It is obtained from the inner bark of several species of…Neuroprotective role of Tinospora cordifolia in MPTP induced Parkinsonian mouse model
Objective: To evaluate the neuroprotective effect of Tinospora cordifolia aqueous extract (TCAE) in Parkinsonian mice. Background: Parkinson’s disease, an age related neurodegenerative disorder, is characterized…Relationship between non-motor symptom symptoms and clinical symptoms in Parkinson’s disease using “Non-Motor Symptom assessment scale for Parkinson’s disease”
Objective: We evaluated the relationship between non-motor symptoms and clinical signs in patients with Parkinson’s disease (PD). Background: Patients with Parkinson's disease (PD) manifest not…The FOsmetpantotenate Replacement Therapy (FORT) Pivotal Trial: Utilization of a Novel Primary Efficacy Outcome in Patients with Pantothenate Kinase-Associated Neurodegeneration
Objective: To describe the methodology and novel primary efficacy outcome measure in the ongoing pivotal FORT trial in patients with pantothenate kinase-associated neurodegeneration (PKAN). Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.