MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Effectiveness of a Multi-disciplinary Parkinson’s Disease (PD) Clinic: A 2-year Prospective Observational Study

    G. Chan, N. Cheung, S. Or, I. Chan, A. Leung, C. Li, D. Chau, C.W. Woo, B. Chee, W.C. Fong (Hong Kong)

    Objective: To evaluate if a multi-disciplinary PD clinic can result in better outcome in PD patients in 2 years. Background: PD is a neurodegenerative disease…
  • 2018 International Congress

    Rationale and Design of an Open-Label, Randomized, 26-Week Study Comparing Levodopa-Carbidopa Intestinal Gel to Optimized Medical Treatment on Non-Motor Symptoms in Patients with Advanced Parkinson’s Disease – INSIGHTS Study

    K. Chaudhuri, D. Weintraub, A. Antonini, W. Robieson, M. Li, K. Chatamra, J. Benesh, M. Facheris (London, United Kingdom)

    Objective: To examine levodopa-carbidopa intestinal gel, LCIG (also known as carbidopa-levodopa enteral suspension in the US), on non-motor symptoms (NMS) compared with individually-optimized, conventional PD…
  • 2018 International Congress

    Oral treatment with JNX3001 protects dopaminergic function in a non-human primate model of Parkinson’s disease alpha-synucleinopathy

    P. Howson, T. Johnston, J. Brotchie, M. Hill, J. Koprich (Toronto, ON, Canada)

    Objective: We evaluated the efficacy of JNX3001 in an aSyn-based macaque model with plasma exposures associated with efficacy in rodents. Background: Alpha-synuclein (aSyn) deposition is…
  • 2018 International Congress

    PROtein, LEucine And vitamin D Enhancing Rehabilitation (PRO-LEADER) in patients with Parkinson’s disease or parkinsonism: A RCT

    M. Barichella, E. Cereda, G. Pinelli, L. Iorio, D. Caroli, I. Masiero, V. Ferri, E. Cassani, C. Bolliri, S. Caronni, P. Ortelli, D. Ferrazzoli, A. Maras, G. Riboldazzi, G. Frazzitta, G. Pezzoli (Milano, Italy)

    Objective: We evaluated the efficacy of a muscle-targeted nutritional support on the outcomes of a multidisciplinary intensive rehabilitation treatment (MIRT). Background: Physical rehabilitation is an…
  • 2018 International Congress

    Dysphagia predicts poor outcome in late-stage Parkinson’s disease

    M. Fabbri, D. Abreu, L. Guedes, M. Rosa, A. Antonini, M. Zibetti, L. Lopiano, J. Fereira, M. Coelho (Lisbon, Portugal)

    Objective: to evaluate the clinical progression and prognostic factors of a late-stage PD (LSPD) population. Background: Parkinson’s disease (PD) disability milestones emerge in an exponential…
  • 2018 International Congress

    A single center retrospective analysis of Opicapone treatment in 90 Parkinson patients

    M. Winterholler, H. Erxleben (Schwarzenbruck, Germany)

    Objective: To evaluate retrospectively the treatment with the novel COMT-inhibitor opicapone (OPC) in a tertiary Parkinson Center the first year after its approval in Germany…
  • 2018 International Congress

    Double-blind controlled trial of Spectramax™ light therapy for the treatment of Parkinson’s disease patients on stable dopaminergic therapy

    A. Videnovic, S. Rutten, W. Croft, H. Erickson, J. Groves, C. Havemann, T. Herrington, S. Hendrix, K. Kieburtz, Y. vander Werf, O. vanden Heuvel (Boston, MA, USA)

    Objective: To evaluate the safety and effectiveness of Spectramax™ specialized bandwidth light therapy (LT) as adjunctive treatment in Parkinson’s disease (PD). Background: Previous studies have…
  • 2018 International Congress

    Frequency-dependent effects of subthalamic deep brain stimulation on motor symptoms in Parkinson’s disease

    D. Su, W. Hu, H. Chen, J. Zhou, T. Feng (Beijing, China)

    Objective: This study aims to investigate whether low-frequency stimulation (LFS) (100Hz, mostly 130 or 150 Hz) in deep brain stimulation (DBS) targeting subthalamic nucleus (STN).…
  • 2018 International Congress

    Intranasal Delivery of Bromocriptine loaded Lipid Nano Carriers for Enhanced Brain Delivery in Parkinson’s disease

    S. V G, P. Vavia (Mumbai, India)

    Objective: The objective of this research work is to develop a lipid nanocarrier system of Bromocriptine and evaluate its increased efficacy in the management of…
  • 2018 International Congress

    Augmented Reality-Based Dance Application on Balance and Mobility of Individuals with Parkinson’s Disease: A Pilot Study

    T. Tunur, K. Rickford, A. DeBlois, E. Horton-Yates, L. Columna (San Marcos, CA, USA)

    Objective: To investigate the acute and long-term effects of a mobile, augmented reality-based extension of Dance for PD® classes on balance and mobility in persons…
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