Relationship between the presence of colonic a-synuclein and MDS research criteria for prodromal PD in patients without manifest motor parkinsonism (PARCAS study)
Objective: The aim of the study was to assess the prevalence of prodromal PD based on the MDS research criteria in a population of patients…Increased bilirubin levels in Parkinson’s disease from southern Spain.
Objective: To evaluate serum bilirubin concentration in Parkinson’s disease (PD) compared to healthy controls (HC) and to investigate its associations with motor and non-motor features…Parkinson’s Disease-Like Pathology in the Rat Brain and Colon Following Methamphetamine Self-Administration
Objective: To determine if Parkinson’s disease (PD)-like pathology occurs in brain and colon following termination of methamphetamine (meth) self-administration. Background: Meth abuse increases the risk…Exploratory Clinical study of role of cerebral dopamine neurotrophic factor (CDNF) mediating endoplasmic reticulum stress (ERS) in Parkinson Disease
Objective: 1: to identify and measure endogenous CDNF levels in peripheral whole blood of healthy control subjects and to examine CNDF expression development profile across the life…The value of the Tau/α-synuclein ratio and TNF-α in cerebrospinal fluid, and of plasma IL-6, in the diagnosis and prognosis of Parkinson’s disease
Objective: To evaluate cerebrospinal fluid (CSF) levels of proteins associated with neuropathological inclusions and ratios among them and CSF and plasma levels of inflammation-related proteins…Evaluation of spike sorting algorithms applied to artificial spikes and to spikes recorded from the Subthalamic Nucleus of PD patients
Objective: To evaluate the variability in spike sorting results using different clustering algorithms Background: Extracellular currents recorded from the Subthalamic Nucleus (STN) of PD patients,…Listen to your heart: ordinal pattern statistics reveal altered cardiac rhythm dynamics in LRRK2-nonmanifesting carriers
Objective: To assess the complexity of heart rate variability (HRV) dynamics in LRRK2-nonmanifesting carriers compared to healthy individuals. Background: Cardiovascular autonomic dysfunction is an early…Pharmacological modulation of mGluR5 improves dyskinesias mediated by D1 but not D2 receptor stimulation.
Objective: To determine whether pharmacological inhibition of metabotropic glutamate receptor type 5 (mGluR5) can improve dyskinesias mediated by D1- or D2-type dopamine (DA) receptors (D1R…Beneficial and Protective Effects of Withania Someniferais On Mice Brain: A Therapeutic Potential Drug for Parkinson’s Disease
Objective: Objective of our study was evaluate effect of Withania Someniferais leaves on Parkinsons brain of mice Background: Parkinson’s disease (PD), an age-related disorder, is…Altered somtatosensory cortex neuronal activity in a rat model of Parkinson`s disease and levodopa-induced dyskinesias
Objective: In this study, we explored the neuronal firing activity of excitatory pyramidal cells and inhibitory interneurons in the forelimb region of the primary somatosensory…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.