Effects of a combined approach with botulinum toxin (BONT) and motor-learning techniques (MLT) on sensori-motor functional connectivity in patients with cervical dystonia (CD)
Objective: Aim of this study is to evaluate sensori-motor connectivity associated with a multimodal BoNT/MLT teratment in CD patients using advanced Resonance Imaging (MRI) techniques.…Postural Stability in Blepharospasm and the Effects of Botulinum Toxin Therapy
Objective: To determine (1) how blepharospasm effects postural stability and (2) to evaluate the efficacy of botulinum toxin therapy (BoNT-A) on static balance in patients…Cervical dystonia – changes in resting state cerebellar connectivity induced by botulinum toxin
Objective: The aim of our study was to compare the connectivity between large-scale resting state networks and the cerebellum before and after treatment initiation. Background:…Disease Modeling of DYT1 Using Patient Induced Pluripotent Stem Cells
Objective: To create a resource of induced pluripotent stem cells (iPSCs) as models for exploring mechanisms of pathogenesis in DYT1 dystonia. Background: DYT1 an autosomal…Phenotypic Heterogeneity and Variability of Nigrostriatal Dopaminergic Function in a Dopa-Responsive Dystonia
Objective: To evaluate presynaptic nigrostriatal dopaminergic function in a Dopa-responsive dystonia (DRD) family with guanosine triphosphate cyclohydrolase 1 (GCH-1) mutation. Background: Mutation of GCH-1 located…Can cerebellar dysfunction help differentiate idiopathic from functional cervical dystonia?
Objective: This study investigated cerebellar function in patients with primary cervical dystonia (CD) and patients with presumed functional dystonia, with the intention to both clarify…Handwriting analysis in Writer’s cramp using a digitizing tablet
Objective: Kinematic analysis of Archimedean spiral drawing in Writer’s cramp (WC) patients compared to healthy participants using a digitizing tablet. Background: Spiral drawing using a…The Prevalence of Dystonic Tremor and Tremor Associated with Dystonia (TAWD) in Patients with Cervical Dystonia
Objective: To investigate the prevalence of dystonic tremor and tremor associated with dystonia (TAWD) in patients with cervical dystonia. Background: The link between dystonia and…Segmentation of neck muscles using ultrasound in cervical dystonia
Objective: Identify neck muscle boundaries using real-time ultrasound in cervical dystonia and relate imaging data to neck muscle structure and function. Background: Identification of individual…Encephalopathy in a Japanese patient with Rapid-Onset Dystonia-Parkinsonism carrying a Novel ATP1A3 mutation
Objective: To investigate underlying pathomechanisms of DYT/PARK-ATP1A3 in Japanese patient with rapid-onset dystonia-parkinsonism (RDP). Background: Mutations in ATP1A3 would lead to development of various neurological…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.