MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2017 International Congress

    Drug utilization characteristics in individuals with early Parkinson’s disease interim analysis of the STEADY-PD III study

    S. Sharma, T. Simuni, B. Greco, K. Biglan, C. Tarolli, K. Hodgeman, D. Oakes, D. Penz (Rochester, NY, USA)

    Objective: To review symptomatic therapy (ST) utilization trends in individuals with early Parkinson’s disease (PD). Background: There are changing trends in ST utilization in early…
  • 2017 International Congress

    Five year longitudinal change in the MDS-UPDRS scores in early Parkinson’s disease participants: Results from the PPMI Study

    T. Simuni, C. Caspell-Garcia, N. Seedorff, C. Coffey, S. Lasch, B. Mollenhauer, C. Tanner, K. Kieburtz, K. Marek (Chicago, IL, USA)

    Objective: To determine the longitudinal change in the Movement Disorder Society –Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) in Parkinson’s disease (PD) participants who were untreated…
  • 2017 International Congress

    Preliminary Report on the MAESTRO Study: A Pilot Study of Mirabegron and Behavioral Modification including Pelvic Floor Exercise for Overactive Bladder in Parkinson Disease.

    S. Ray, D. Burdick, A. Griffith, P. Agarwal (Kirkland, WA, USA)

    Objective: To report enrollment and tolerability data of mirabegron treatment in PD patients with OAB. Background: Lower urinary tract symptoms in PD have an estimated…
  • 2017 International Congress

    The Critical Path for Parkinson’s Consortium: Understanding Motor Disease Progression Through Quantitative Medicine

    K. Romero, D. Conrado, B. Corrigan, K. Tsai, M. Ahamadi, S. Macha, V. Sinha, I. Watson, M. Bani, P. Muglia, V. Kern, C. Williams-Gray, D. Grosset, M. Hu, D. Burn, R. Lawson, K. Marek, A. Roach, D. Stephenson, T. Nicholas (Tucson, AZ, USA)

    Objective: Develop a quantitative tool to optimize the definition of entry criteria, enrichment strategies and stratification approaches, and submit for formal regulatory endorsement at FDA…
  • 2017 International Congress

    Programming of deep brain stimulators in Parkinson’s disease with early motor complications (EARLYSTIM-study)

    K. Knudsen, J.-L. Houeto, P. Krack, J. Rau, C. Schade-Brittinger, A. Schnitzler, W.M.M. Schuepbach, L. Timmermann, L. Tonder, G. Deuschl (Kiel, Germany)

    Objective: Recently the EARLYSTIM study showed the superior effect of subthalamic stimulation to best medical treatment in Parkinson`s disease with early motor complications.  Background: EARLYSTIM…
  • 2017 International Congress

    Innovative recruitment strategies accelerate enrollment of genetic mutation carriers in the Parkinson’s Progression Markers Initiative (PPMI)

    V. Arnedo, S. Lasch, T. Foroud, L. Heathers, J. Martorelli, C. Halter, N. Ryerson, J. Verbrugge, L. Cook, K. Marek (New York, NY, USA)

    Objective: Determine feasibility of digital recruitment strategies, centralized screening, and a dedicated referral coordinator to enroll participants with LRRK2 or GBA mutations into PPMI, a…
  • 2017 International Congress

    Proprioceptive Focal Stimulation (Equistasi®) may improve gait in severe Parkinson’s disease patients. Gait Analysis double-blind, double-dummy randomized study

    A. Peppe, S. Paravati, g. Chini, P. Paone (Roma, Italy)

    Objective: Object of the study was to evaluate the efficacy of  Propriocettive Focal Stimulation on Gait in  severe Parkinson disease patients by  randomized Blind double…
  • 2017 International Congress

    Study Design for a Multi-Modal Approach to Understanding Parkinson’s Disease: The Personalized Parkinson Project

    W. Marks, Jr., L. Evers, M. Faber, M. Verbeek, N. de Vries, B. Bloem (South San Francisco, CA, USA)

    Objective: We aim to create a longitudinal dataset of clinical, molecular, imaging, and continuous wearable sensor-based data from a representative Parkinson’s disease (PD) cohort. Data…
  • 2017 International Congress

    Improvement in attention/memory domains in advanced Parkinson’s disease patients treated with levodopa-carbidopa intestinal gel is associated with better quality of life

    D. Standaert, R. Rodriguez, J. Slevin, M. Lobatz, C. Hall, M. Facheris, J. Benesh, S. Dubow (Birmingham, AL, USA)

    Objective: To evaluate the relationship between non-motor symptom (NMS) severity, quality of life (QoL), and activities of daily living (ADL) in advanced Parkinson’s disease (PD)…
  • 2017 International Congress

    Safety of levodopa-carbidopa intestinal gel treatment in advanced Parkinson’s disease patients receiving ≥ 2000 mg daily dose of levodopa

    C. Zadikoff, J. Boyd, S. Dubow, L. Bergmann, W. Robieson, H. Ijacu, J. Benesh (Chicago, IL, USA)

    Objective: To examine the safety of levodopa-carbidopa intestinal gel treatment (LCIG, carbidopa-levodopa enteral suspension in the US) in advanced Parkinson’s disease (PD) patients that received…
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