Manual and Verbal guidance during the balance training based in virtual reality is essential for therapeutic results in people with Parkinson’s disease: a randomized clinical trial
Objective: To compare the effects of balance training in Virtual Reality (VR) supported by manual and verbal guidance (MVG) versus an identical training in absence…Randomized Parkinson’s Trial of GDNF Administered via Intermittent Intraputamenal Convection-Enhanced Delivery.
Objective: Assesing the neurorestorative effect of GDNF. Background: GDNF is a potent neurotrophic factor. A previous placebo-controlled trial, however, at 6 months, failed to demonstrate…The Importance of Ultrasonographic Evaluation in the Diagnosis of Dysphagia in Parkinson Disease
Objective: Dysphagia occur frequently in Parkinson’s disease. It include usually some problems to pharyngeal phase. Background: The aim of this study was to compare the…A Preliminary Study: Validity and Reliability of Parkinson Fatigue Scale (PFS) in Turkish Patients with Parkinson’s Disease (PD)
Objective: The purpose of this study was to investigate the validity and reliability of the Turkish version of PFS. Background: The PFS is a 16-item…The effect of early STN-DBS in PD patients on axial symptoms: a 2-year randomized controlled trial (EARLYSTIM-Gait analysis)
Objective: This study assesses the effect of STN-DBS in early PD patients on axial symptoms compared to BMT. Background: In well-selected candidates, STN-DBS offers symptom…A Preliminary Study: Validity and Reliability of Turkish Version of Fatigue Severity Scale (FSS) in Patients with Parkinson’s Disease (PD)
Objective: The aim of this study was to evaluate the validity and reliability of the Turkish version of FSS. Background: Fatigue is a frequent, non-motor…Physical activity habits in early Parkinson’s disease and healthy controls
Objective: Investigate the physical activity habits of Parkinson’s disease (PD) and healthy control (HC) participants of the PPMI cohort. Background: Exercise can improve the motor…The occurrence of dopamine-responsive and dopamine-resistant resting tremor in Parkinson’s disease
Objective: To investigate dopamine-responsiveness of resting tremor in Parkinson’s disease Background: Unlike the core Parkinson motor symptom, bradykinesia, resting tremor has a variable response to…How to switch from Entacapone to Opicapone based on BIPARK-I study experience
Objective: To clarify how easily can entacapone (ENT) be switched to opicapone (OPC), in levodopa-treated patients with Parkinson’s disease (PD) and motor-fluctuations. Background: OPC, a…Effect of food on Opicapone pharmacokinetics and pharmacodynamics
Objective: To characterize the effect of food on the pharmacokinetics (PK) and pharmacodynamics (PD) of opicapone (OPC) after single and repeated doses. Background: OPC, a…