Decision-making process for opicapone’s bedtime regimen
Objective: To clarify the decision-making process for opicapone’s bedtime regímen. Background: OPC, a new once-daily COMT inhibitor, was shown to be effective in the treatment…Levodopa/carbidopa Intestinal Gel Can Improve Both Motor and Non-Motor Experiences of Daily Living in Parkinson’s Disease: An Open-Label Study
Objective: : Our aim was to determine if the MDS-UPDRS and UDysRS could detect improvement in the experiences of daily living following 1-year LCIG treatment.…Towards Responsive Deep Brain Stimulation for Medically Refractory Freezing of Gait in Parkinson’s Disease
Objective: Medically refractory FoG presents an unmet and pressing need to develop novel therapeutic strategies. We seek to describe the electrophysiology of the pedunculopontine nucleus…Tozadenant phase 3 study (TOZ-PD) in Parkinson’s disease patients with motor fluctuations: baseline characteristics
Objective: To describe the baseline characteristics of the TOZ-PD study population. Background: Tozadenant is an adenosine A2A antagonist under investigation as an adjunct to levodopa…Associating patient impression of improvement with efficacy endpoints in Parkinson’s disease: A post-hoc analysis of a tozadenant study
Objective: To evaluate whether patient perceived improvement of Parkinson’s disease (PD) symptoms was associated with improvement in efficacy endpoints (mean daily OFF time and ON…A Phase 3 Study of isradipine as a disease modifying agent in patients with early Parkinson’s disease (STEADY-PD III): Baseline characteristics and study update
Objective: To evaluate the efficacy of isradipine 10 mg daily to slow progression of disability in early PD. Background: Isradipine, a dihydropyridine calcium channel antagonist,…The effect of dance and Nordic Walking on balance, gait and motor function in Parkinson’s disease
Objective: To present two rehabilitation programs based on dance and Nordic Walking (NW) for patients with Parkinson’s disease (PD) and their effects. Background: Parkinson’s disease…Feasibility of using a smartphone application for the objective evaluation of Parkinson disease
Objective: To determine the feasibility, reliability, and value of using a smartphone application to longitudinally track motor and non-motor features of Parkinson disease (PD). Further,…Istradefylline and Preladenant as adjuvant therapies for Patients with Parkinson’s disease
Objective: The aim of this meta-analysis is to synthesize evidence about the efficacy of the adenosine receptor antagonists (Istradefylline and Preladenant) for patients with Parkinson’s…DBS Plus: Investigating cell therapy and deep brain stimulation as an approach to alter disease progression and treat motor and non-motor symptoms of Parkinson’s disease
Objective: Investigate safety, feasibility, and potential efficacy of cell therapy combined with DBS to treat and modify symptoms and progression of PD. Background: Our strategy…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.