Efficacy and Safety of Therapeutic Interventions to Treat Motor Symptoms in Late Stage Parkinson’s Disease: A Systematic Review
Objective: Evaluate the efficacy and safety of therapeutic interventions to treat the motor symptoms in late stage PD. Background: PD patients in late stage are…Quantitative demonstration of the efficacy of rotigotine transdermal patch in the treatment of nocturnal hypokinesia: A randomized, placebo-controlled trial using an axial inertial sensor
Objective: To evaluate the efficacy of rotigotine transdermal patch, using a wearable sensor, to treat PD patients with nocturnal immobility. Background: Nocturnal hypokinesia is a…Effect of deep brain stimulation on visuospatial impairment in Parkinson’s disease
Objective: We evaluated postoperative change of visuospatial impairment in the patients with Parkinson’s disease (PD) underwent deep brain stimulation (DBS) to assess the impact of…A novel paradigm of variable frequency deep brain stimulation to improve freezing of gait in Parkinson’s disease
Objective: To determine the effects of a novel deep brain stimulation (DBS) paradigm of combining high and low frequency stimulation in varying patterns (VFS) for…Medical Treatment Termination in Parkinson’s Disease Patients after Hepad Therapy: A Case Series
Objective: To report seven clinical cases of treatment completion and improvement of symptoms after a PD therapy regimen that included Hepad. Background: DOPA decarboxylase inhibitor…Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson’s disease
Objective: To employ a combination of elemental concentrations in the cerebrospinal fluid (CSF) to identify a diagnostic biomarker profile differentiating patients with idiopathic Parkinson´s disease…Improving Clinical Trials Through Patient Input: Outcomes of a Partnership Between Pfizer and the Parkinson’s Disease Foundation
Objective: To identify the outcomes of the partnership between Pfizer and the Parkinson’s Disease Foundation (PDF), which was designed to 1. increase understanding of the…Functional role of the cerebellum in Parkinson’s disease : a PET-Study
Objective: The aim of this study is to confirm the hypothesis of a functional involvement of the cerebellum in Parkinson's disease according to a tri-compartmental…Deep Brain Stimulation of Subthalamic Nucleus Selectively Modulates Striato-Thalamo-Cortical Circuit in Parkinson’s Disease: a Systematic Review and ALE Meta-analysis
Objective: To investigate pooled effect of STN-DBS effect on brain activity in Parkinson’s disease (PD), and to address the result inconsistency across previous functional image studies.…Impaired sensorimotor and visual networks in drug naive Parkinson’s disease based on graph theoretical analysis
Objective: We aim to investigate topographic structure in drug naive patients with Parkinson’s disease (PD). Background: Resting state functional magnetic resonance imaging (rs-fMRI) provides valuable…