The comparative clinical analysis of sleep patterns in patients with Amyotrophic Lateral Sclerosis and Parkinson’s disease
Objective: We seek to investigate the nighttime sleep pattern of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and primary Parkinson's disease (PD). Background: Sleep disorders…Fatigue and depression are predictors of the tremor form of Parkinson’s disease
Objective: The principal objective is to study the relationship between fatigue and depression with the peculiarities of the progress of PD. Background: Parkinson's disease (PD)…Odor identification in PD patients and controls in Estonian cohort
Objective: To evaluate odors that discriminate Parkinson patients from healthy persons. Background: More than 90% of PD patients are diagnosed with olfactory impairment. The investigation…Nonlinearities in outcome-specific hazard of motor and nonmotor long-term complications of Parkinson’s disease
Objective: To estimate the specific hazard of motor and nonmotor milestones of Parkinson's disease (PD) progression in the long term. Background: Parkinson’s disease greatly varies…Interaction of amyloidogenic proteins in pancreatic β cells from subjects with synuclenopathies
Objective: We have investigated whether deposits of phosphorylated α-synuclein might be present in pancreatic tissue of subjects with synucleinopathies. Background: Parkinson’s disease patients experience a…Long-term efficacy and safety of incobotulinumtoxinA treatment for sialorrhea in Parkinson’s disease and other neurologic conditions
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with a 48-week extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 U or…Visual deficits of self-motion perception in Parkinson’s disease
Objective: To investigate unisensory and multisensory self-motion perception mediated by the visual and vestibular systems in PD. Background: Parkinson's disease (PD) is classically characterized by…Single-centre open label exploratory phase IIb pilot study of exogenous oral Melatonin for the treatment of Nocturia in adults with Parkinson’s disease
Objective: To evaluate the effect of melatonin on nocturia. Background: Nocturia is one of the commonest non motor symptoms in Parkinsons’ disease (PD), and has…Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with an extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U…Vowel characteristics associated with Parkinson’s disease in Cantonese
Objective: Dopaminergic treatment has been reported to help motor problem associated with Parkinson's disease (PD), but not speech motor. The current study examined vowel articulation…
