Profound reduction of DAT-SPECT signal in multiple system atrophy (MSA)
Objective: To evaluate the extent of degeneration in dopamine nerve terminal in striatum in the patients with MSA-P and MSA-C, and to compare the progression…Can the level of CSF Neurofilament Light Chain predict disease progression in Progressive Supranuclear Palsy?
Objective: To investigate whether the level of CSF Neurofilament Light Chain (NFL) can predict the speed of disease progression in patients with Progressive Supranuclear Palsy…Differential diagnosis of Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: The description of differential diagnostic features of PSP and PD in order to improve the diagnosis and the differential diagnosis of these diseases. Background:…Evaluation of a Radiographic Marker as a Diagnostic Tool For Progressive Supranuclear Palsy
Objective: To evaluate the sensitivity and specificity of a radiographic marker, midbrain to pons ratio, in brain MRI of Progressive Supranuclear Palsy (PSP) patients as…Progression of milestones by clinical types in progressive supranuclear palsy: a longitudinal observational study of a cohort of patients with PSP/CBD (the JALPAC project)
Objective: To elucidate the natural history of the PSP clinical phenotype Background: Recently, various clinical types of PSP have been reported, but details on their…Impulse control disorders in Parkinson’s disease; description of a New Zealand cohort
Objective: Impulse control disorders (ICDS) are a recognised complication of dopaminergic therapy for Parkinson’s disease. We wanted to assess the rates of ICDs in New…Brain metabolic patterns in progressive supranuclear palsy phenotypes
Objective: To describe changes in cerebral glucose metabolism in patients with different described clinical phenotypes of PSP and to correlate them with the clinical manifestations of the disease. Background:…Mutational analysis of COQ2 in Chinese patients with multiple-system atrophy
Objective: To investigate the involvement of COQ2 variants in Chinese sporadic cases with multiple-system atrophy. Background: Multiple-system atrophy (MSA) is a rapidly progressive neurodegenerative disease…Gait and Cognition in Progressive Supranuclear Palsy: A Significant Association
Objective: In this study we explored the association between gait parameters and cognitive function of PSP. Background: Gait and cognition are interrelated in patients with…Utility of THK-5351 tau-PET for differential diagnosis in patients with hypokinetic-rigid syndromes.
Objective: The objective of our study is to investigate the use of THK-5351 tau- PET-imaging as an additional tool for differential diagnosis in hypokinetic-rigid syndromes suggestive…
