Effect of Droxidopa Treatment on Fear of Falling in Patients With Neurogenic Orthostatic Hypotension: Clinical Trial and “Real World” Results
Objective: To assess the impact of droxidopa on fear of falling in patients with symptomatic neurogenic orthostatic hypotension (nOH) in 2 studies. Background: nOH results…Interim Results of an Ongoing Open-label Safety Study of ADS-5102 (amantadine hydrochloride) Extended-Release Capsules for Treatment of Levodopa-Induced Dyskinesia (LID) (EASE LID 2 Study)
Objective: Characterize the long-term safety and tolerability of 340 mg of ADS-5102 administered once daily at bedtime, for the treatment of LID in Parkinson’s disease…Parkinsonics – A Prospective, Randomized, Blinded, Cross-Over Trial of Group Singing for Motor and Non-Motor Symptoms in Idiopathic Parkinson Disease (PD)
Objective: To assess the effects of weekly group singing on PD patients’ objective vocal and motoric function, cognition, mood, self-efficacy and quality of life. Background:…Correlation of Electrode Position and Clinical Outcomes in Globus Pallidus Stimulation for Dystonia
Objective: The aim of this study was to determine the discrepancies between the final location of the contacts in the GPi and the targets that…Gpi DBS for Dystonia in Pediatric Patients
Objective: Dystonia is a movement disorder in which involuntary sustained or intermittent muscle contractions cause twisting and repetitive movements, abnormal postures, or both. It can…Noninvasive cerebellar stimulation for adults with cervical dystonia
Objective: To examine whether a 5 day treatment period of anodal transcranial direct current stimulation (a-tDCS) over the cerebellum would improve patients’ symptoms and alter…Abnormal patterns of action selection in the dominant motor cortex in writer’s cramp
Objective: To test if (1) abnormal right dorsal premotor cortex (dPMC) to left primary motor cortex (M1) interaction during writing with right hand contributes to…Regional differences may influence the drivers of change in Toronto Western Spasmodic Rating Scale (TWSTRS) scores following botulinum toxin treatment: Analysis of an international observational study
Objective: Investigate the drivers for change in Toronto Western Spasmodic Rating Scale (TWSTRS) scores in subjects with cervical dystonia (CD) following a single injection of…Cost-utility analysis of flexible interval incobotulinumtoxinA versus onabotulinumtoxinA in the management of blepharospasm and cervical dystonia in Ontario, Canada.
Objective: To carry out a cost-utility analysis for IncoBTX administered with flexible treatment intervals compared to OnaBTX in the management of BL and CD from…A Pilot Multiparametric MEG Study of coherence in generalized and cervical dystonia
Objective: To explore functional connectivity at network level with MEG, pre and post-administration of medications, in generalized and cervical dystonia. Background: The underlying mechanisms of…
