Disease modeling for Perry syndrome using patient induced pluripotent stem cells
Objective: To develop a novel model of Perry syndrome using induced pluripotent stem cell (iPSC)-derived neurons. Background: Perry syndrome is a rare autosomal dominant disorder…The Use of Atypical Antipsychotics in Depression and Anxiety may Unmask Parkinson’s Disease: A Retrospective Chart Review
Objective: Characterize the population with parkinsonism and exposure to antipsychotics who underwent dopamine transporter single-photon emission computed tomography (DATSPECT). Background: Atypical antipsychotics are used in …Pregnancy and Parkinson’s disease: A review and update
Objective: To investigate the literature on pregnancy in the setting of Parkinson’s disease (PD) in order to better understand and treat women who become pregnant.…Patients affected by functional motor symptoms are not liars: an experimental deception study with the Guilty Knowledge Task
Objective: To assess deception in patients affected by functional motor symptoms. Background: The relationship between functional neurological symptoms (FNS) and feigning is not an easy…Baseline predictors for clinical progression after 48 month follow-up in early Parkinson’s disease from the DeNoPa cohort
Objective: To analyze clinical progression at enrolment in drug-naïve Parkinson’s disease (PD) subjects over 48 months of follow-up, we describe the annual rate of progression…Extrapyramidal signs in neurosarcoidosis versus multiple sclerosis: is TNF alpha the link?
Objective: To assess the frequency of extrapyramidal signs in patients with NS compared to patients with MS. Background: Specific inflammatory pathways and specifically Tumor necrosis…Falls in Parkinson’s disease are related to delayed recovery time after unexpected external perturbations
Objective: The aim of this study was to analyze the postural adjustments in fallers and non-fallers Parkinson’s disease (PD) patients. Background: Adequate reactive postural response…Motor Heterogeneity in Parkinson’s Disease: A Bayesian Perspective
Objective: To identify motor symptom subtypes in idiopathic Parkinson’s disease (PD) using a Bayesian analytic approach to latent profile analysis. Background: Several subtypes of Parkinson’s…Oscillatory Activity in the Nucleus Basalis of Meynert
Objective: Characterize oscillatory activity in and around the nucleus basalis of Meynert (NBM). Background: The NBM is the major source of cholinergic innervation to the…New method to evaluate new motor skill learning
Objective: To present a novel approach to assessing improvements in new motor skill learning. Background: Several methods have been employed over the years to try…
