Effects of a Parkinson-Specific, Interdisciplinary Approach, To Inpatient Rehabilitation
Objective: To demonstrate the effects of an interdisciplinary team approach in the evaluation and treatment of Parkinson’s disease (PD) patients, during inpatient rehabilitation. Background: PD…Antiparkinson and antioxidant effect of N-Methanesulfonylpyrazolinyl substituted Heterosteroids in LPS induced Neuroinflammation Model of Rats
Objective: This present study is mainly focused at design and synthesis of new therapeutically useful steroidal neuroprotective agents against neuroinflammation which involved in the progression…Active Arms: a randomized controlled trial of an interactive videogame for people with Parkinson’s disease
Objective: To determine if home-based exergames targeting the upper extremities (UE) improves arm and hand activities and impairments in people with PD. To establish the…Study Design of an Efficacy and Safety Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of APL-130277 in the Treatment of OFF Episodes (CTH-300)
Objective: To review the unique features of the ongoing Phase 3 trial for APL-130277. Background: Patients with Parkinson’s disease (PD) frequently develop problematic OFF episodes…Noladin ether attenuates MPTP -induced motor deficit by abrogating pro-inflammatory cytokines and striatal neurochemical alterations in rats
Objective: The present study was designed to investigate the therapeutic potential of noladin ether- a putative endocannabinoid against MPTP-induced behavioral, biochemical and neurochemical alterations in…Nilotinib differentially affects oligomeric α-synuclein and reduces phosphorylated neurofilaments and motor symptoms in Parkinson’s disease with dementia and Lewy body dementia
Objective: This is a retrospective biomarker study of an open-label clinical study to examine the safety and efficacy of lower doses (<50% of CML dose)…A single aerobic exercise session of treadmill increases BDNF levels in Parkinson’s disease patients
Objective: The aim of this study was to investigate the effect of a single session moderate-intensity treadmill exercise on serum levels brain-derived neurotrophic factor (BDNF)…Slow Release Fixed Dose Combination of Low Doses Pramipexole and Rasagiline (P2B001) for the Treatment of Early Parkinson’s Disease (PD).
Objective: Evaluation of the efficacy and safety of a slow release low dose combination of pramipexole (PPX) and rasagiline (RAS) (P2B001) in a prospective double-blind…Vitamin D and Clinical Phenotypes of Parkinson’s Disease
Objective: To explore the relationship of clinical phenotypes of Parkinson's disease (PD) with vitamin D levels in Veterans diagnosed with PD. Background: PD is a heterogeneous neurodegenerative…Istradefylline for daytime sleepiness and sleep disturbances in patients with Parkinson’s disease: an open-label, 3-month study
Objective: To evaluate the effect of istradefylline on daytime sleepiness and sleep disturbances as well as motor symptoms in patients with Parkinson’s disease (PD) in…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.