How will new technology change deep brain stimulation programming?
Objective: Assess the ways in which decision support tools and directional leads are affecting DBS programming. Background: The typical approach to DBS programming has changed…Voice Therapy Normalizes Feedforward and Feedback Networks of the Speech Motor System
Objective: The aim of the study was to isolate the specific effects of the training target of The Lee Silverman Voice Therapy (LSVT) in Parkinson’s…Study in Parkinson’s Disease of Exercise (SPARX): A Randomized, Controlled Futility Trial
Objective: Our first objective was to determine whether people with de novo Parkinson’s disease (PD) are able to exercise at either 60-65% maximal heart rate…Four year outcomes of a prospective, multi-center trial evaluating Deep Brain Stimulation with a new multiple-source, constant-current rechargeable system in Parkinson’s disease
Objective: To evaluate the four year, long-term follow up results of patients in the VANTAGE clinical study that employed multiple independent current control (MICC) Deep Brain…Istradefylline improves not only motor symptoms but also sleep disturbance, daytime sleepiness, and QOL of Parkinson’s disease patients.
Objective: This study analyzed the clinical effectiveness of istradefylline in terms of sleep disturbance in Parkinson’s disease (PD) patients. Background: A selective adenosine A2A receptor…Improving Racial and Ethnic Diversity in Parkinson`s Disease Clinical Trials
Objective: To identify and overcome challenges to recruiting minorities in Parkinson's Disease experimental therapeutic trials. Background: Inadequate representation of ethnic and minority population poses substantial…Deep brain stimulation in Parkinson’s disease: Outcome after more than nine years
Objective: The aim of this study is to examine the long-term effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson’s disease…Alternations of Metabolic Profile and Kynurenine Metabolism in the Plasma of Parkinson’s Disease
Objective: The purpose of this study was to identify potential plasma metabolic biomarkers for Parkinson’s disease (PD) Background: PD, characterized by a slowness of movement…Observational study of the effectiveness and tolerability of rotigotine+levodopa therapy in older vs younger Parkinson’s disease patients
Objective: Prospective non-interventional study conducted in routine clinical practice (PD0013; NCT02227355) to compare effectiveness and tolerability of rotigotine+levodopa (RTG+Ldopa) in Parkinson’s disease (PD) patients aged…Factors associated with perceived walking difficulties in people with Parkinson’s disease
Objective: To investigate factors that independently contribute to perceived walking difficulties in people with Parkinson’s disease (PD). Background: Despite that walking difficulties are common in…
