5-year results from the NSTAPS trial: comparing bilateral deep brain stimulation of the globus pallidus pars interna versus the subthalamic nucleus for advanced Parkinson’s disease.
Objective: Comparing motor, cognitive, and psychiatric outcome 5 years after bilateral deep brain stimulation (DBS) of the globus pallidus pars interna (GPi) and the subthalamic…ND0612 (levodopa/carbidopa for subcutaneous infusion) achieves stable levodopa plasma levels when administered in low and high doses in patients with PD
Objective: Characterize the levodopa pharmacokinetic profile derived from continuous subcutaneous (SC) administration of ND0612. Background: Continuous levodopa/carbidopa (LD/CD) infusion is considered the optimal delivery route…Early morning OFF problems are common in PD patients attending a routine clinical appointment
Objective: To characterize early morning OFF problems in consecutive PD patients attending a routine clinical appointment. Background: In PD patients with motor fluctuations, total daily…Tandem Standing
Objective: The aim of this study is to learn, patients who can’t make tandem standing fall more or not? Background: Falls occur more often with…Sentence comprehension in Slovak speaking patients with Parkinson´s disease – preliminary results
Objective: The aim of our research was to analyze comprehension of various syntactic constructions in Slovak-speaking PD-ND patients . We were particularly interested in exploring…Aquatic Physical Exercises: Balance in People with Parkinson’s Disease
Objective: to evaluate the repercussion of an aquatic physical exercise program on the body balance of people with Parkinson's disease (PD) in stages 2, 5…ND0701: A new concentrated formulation of Apomorphine for continuous subcutaneous administration – human PK data
Objective: To evaluate the PK and relative bioavailability of ND0701, a subcutaneously (SC) infused apomorphine-base product candidate, and a commercial apomorphine-HCl product. The secondary objective…Spinal cord stimulation as therapeutic option in gait disorder in Parkinson disease.
Objective: We aim to study the effect of spinal cord stimulation over gait in parkinson disease without pain nor neuropathy. Background: Axial symptoms in the course…Identification of the optimal carbidopa concentration in subcutaneously administered ND0612
Objective: To identify the concentration of subcutaneous (SC) carbidopa (CD) that provides optimal bioavailability of a concomitant fixed concentration of levodopa (LD) when administered via…Focused ultrasound subthalamotomy for Parkinson’s disease: A pilot study
Objective: To evaluate feasibility, safety and effectiveness of unilateral subthalamotomy performed with MRIgHIFU to treat the cardinal motor features of PD Background: Ablative functional neurosurgery for…
