Generation and characterization of iPSC-derived nigral dopaminergic and pyramidal glutamatergic neurons from patients affected by multiple system atrophy
Objective: The aim of the present study is to generate dopaminergic and pyramidal neurons from iPSCs of MSA patients in order to establish an in…Cognitive impairment in patients with progressive supranuclear palsy and multiple system atrophy
Objective: Assessment, description and mutual comparison of cognitive impairment in patients with progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). Background: In most recent…Zolpidem ameliorates the freezing of gait in a patient with PAGF (pure akinesia with freezing of gait)-the possible neural mechanism
Objective: To investigate the possible mechanism of amelioration of freezing of gait (FOG) in a patient with PAGF (Pure Akinesia with Freezing of Gait) by…Composite autonomic symptom scale-31 (COMPASS-31) is useful for evaluation of autonomic dysfunction in patients with parkinsonism
Objective: To investigate the usefulness of composite autonomic symptom scale 31 (COMPASS-31) in patients with parkinsonism by comparing COMPASS-31 between PD and MSA patients, and…Modeling trajectories of brain damage in progressive supranuclear palsy: A longitudinal multimodal MRI study
Objective: To explore longitudinally clinical, cognitive, and neuroimaging changes in patients with progressive supranuclear palsy syndrome (PSPs). Background: PSP is a progressive neurodegenerative disease. Longitudinal…Three cases of neuronal intranuclear inclusion disease (NIID)
Objective: Here, we present three NIID cases. One of them, autopsy was performed. Background: Neuronal intranuclear inclusion disease (NIID)(OMIM 603472) is a neurodegenerative disorder characterized…Atypical Parkinsonian disorders: Insights for a differential diagnosis through the analysis of oculomotor profile in MSA, PSP and CBD patients
Objective: To determine peculiar changes in oculomotor profile that may help in distinguishing atypical parkinsonism with overlapping clinical features. Background: Atypical Parkinsonian disorders (APDs) include…Creative thinking and parkinsonism: Preliminary clinical data on the role of frontal area
Objective: To evaluate divergent thinking (DT) by means of Abbreviated Torrance Test for Adults (ATTA) in Parkinsonism (PKS) with different deficit in cognitive functions. Background:…Deceleration capacity of heart rate indicates autonomic dysfunction in patients with PSP
Objective: The study focuses on assessing cardiovascular autonomic dysfunction in patients with different atypical Parkinsonian syndromes compared to healthy controls using the heart rate deceleration…Prevalence and characterisation of vocal fold motion impairment (VFMI) in patients with multiple system atrophy
Objective: Our objective was to describe the characteristics of vocal fold motion impairments (VFMI) in MSA and to determine whether they had a diagnostic and…
