Clinical Significance of Imaging Markers for Cerebellar Ataxia and Parkinsonism in Multiple System Atrophy
Objective: To clarify the interactions among clinical features and imaging markers, and to identify factors contributing to disease severity in MSA. Background: Multiple system atrophy…Assessing Concordance Between Clinical judgment And 5-2-1 Criteria In Advanced Parkinsons Disease
Objective: 1. Assess how accurately clinicians diagnose Advanced Parkinson’s Disease (APD) in a routine clinical setting2. Evaluate concordance between 5-2-1 criteria and clinician judgement, including…Quantitative susceptibility mapping with 7T MRI as a novel imaging biomarker for periventricular degeneration in normal pressure hydrocephalus: A pilot study
Objective: We try to investigate periventricular susceptibility alterations using QSM to establish a novel, accurate early imaging biomarker for NPH. Background: Normal pressure hydrocephalus (NPH)…Reducing Cost and Operative Time in DBS with a Consolidated Workflow: A Time-Driven Activity-Based Costing Analysis
Objective: To show that a consolidated patient specific workflow significantly improved operative efficiency and reduced personnel costs for deep brain stimulation (DBS) implantation, without compromise…Identification of Alpha-synuclein Pathology in Idiopathic Rapid Eye Movement Sleep Disorder Participants by Seed Amplification Assay
Objective: To assess correlations between cerebrospinal fluid (CSF) α-synuclein seed amplification assay (synSAA) and the phenoconversion rate, timing, and final diagnosis of idiopathic rapid eye…Sensitivity of AI-Derived Video-Based Digital Biomarkers to Motor Progression in Parkinson’s Disease
Objective: To determine whether video-based digital biomarkers derived from standardized motor tasks are sensitive to longitudinal progression in Parkinson’s disease (PD). Background: Bradykinesia is a…Lead Asymmetry and Axial Symptom Response to Deep Brain Stimulation in Parkinson’s Disease: A Synthetic Pilot Modeling Study
Objective: To evaluate whether bilateral DBS lead placement asymmetry captures clinically meaningful correlates of motor outcomes, particularly freezing of gait (FoG) and balance to establish…A highly specific skin α-synuclein seed amplification assay for screening of synucleionpathies
Objective: To evaluate the performance of a skin α-synuclein seed amplification assay (skin_synSAA) as a screening test using samples from movement disorder subjects with uncertain…Personality Dynamics and Cognitive Impairment and Related Neuropsychiatric Symptoms in Patience with Different Movement Disorders
Objective: To find out the prevalence of Eysenck’s Personality type among the patients with different movement disorders.To find out the relationship between cognitive impairments and…Metabolic-Structural Patterns Across Progressive Supranuclear Palsy Clinical Variants: a Multimodal PET-MRI Study
Objective: To characterize patterns of regional glucose hypometabolism on Fluorodeoxyglucose (FDG)-PET and structural atrophy on MRI across clinical variants of progressive supranuclear palsy (PSP). Background:…
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