Association between Smoking and LRRK2 Variants on Parkinson’s Disease Risk
Objective: To examine whether smoking modifies the association between protective LRRK2 variants (N551K and R1398H) and the risk of Parkinson’s disease in a case-control cohort.…Translating Real-World Parkinsonian Facial Kinematics onto Diverse Digital Avatars
Objective: To support the development of a smart textile with facial sensors and present a novel continuous monitoring approach, we derived and rendered digital twins…Impact of Hula on Balance Outcomes in Parkinson’s Disease
Objective: This study aims to determine the impact of a 12-week Hula program on balance in patients with Parkinson’s Disease (PD) and to investigate changes…Prevalence of sarcopenic obesity and its association with non-motor symptoms in early Parkinson’s disease
Objective: To investigate the prevalence of sarcopenia, obesity, and sarcopenic obesity (SO) and their associations with non-motor symptoms in patients with early Parkinson’s disease (PD).…Determinants of Tremor Control Across Severity Levels Following GPi-Deep Brain Stimulation in Parkinson’s Disease
Objective: To compare clinical, stimulation-related, and anatomical determinants of tremor outcome after GPi DBS, between PD patients with severe and mild-moderate tremor. Background: Parkinson’s disease…Determinant factor of tremor recurrence after Vim-FUS in ET and tremor-dominant PD
Objective: To identify clinical and technical predictors of recurrence of tremor in our own cohort of ET and TDPD patients undergoing Vim-FUS Background: Vim-FUS improves…Integrated Digital Monitoring and Outpatient Clinical Care Management Program for Parkinson Disease
Objective: Examine whether digital monitoring within Advanced Primary Care Management (APCM) can detect between-visit change, prompt care-plan updates, and streamline longitudinal management for medically complex…Validation of an Objective Parkinson’s Disease Digital Assessment Tool in Individuals with PD and Healthy Controls
Objective: To validate the sensitivity and accuracy of a video-based motor assessment platform (PRIMS) against a panel of expert MDS-UPDRS reviewers. Background: The platform is…Cholinergic Systems Changes Associated with Freezing of Gait in Progressive Supranuclear Palsy
Objective: To investigate whether distinctive cholinergic system changes are associated with FoG in PSP patients. Background: Freezing of gait (FoG) is a profound mobility disturbance…DJ-1 (PARK7) Heterozygous Mutation and Early-Onset Parkinson’s Disease: A Chilean Case Report and Literature Review
Objective: We report a Chilean patient with childhood-onset Parkinson’s disease (PD) carrying a single heterozygous PARK7 (DJ-1) mutation and review its clinical and pathophysiological relevance.…
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