Digital Prediagnostic Mobility and Autonomic Trajectories in a Large Parkinson Disease Network
Objective: To evaluate whether digital mobility and autonomic trajectories detect prediagnostic decline beyond normative aging. Background: Identifying individuals in prodromal Parkinson disease who are nearing…Cholinergic Systems Changes Associated with Freezing of Gait in Progressive Supranuclear Palsy
Objective: To investigate whether distinctive cholinergic system changes are associated with FoG in PSP patients. Background: Freezing of gait (FoG) is a profound mobility disturbance…Dual-Site Transcranial Magnetic Stimulation Ameliorates Freezing of Gait in Parkinson’s Disease by Remodeling Cortical Excitatory-Inhibitory Balance and White Matter Microstructure: A Randomized Controlled Trial
Objective: To investigate whether dual-site [DS, primary motor cortex (M1) + supplementary motor area (SMA)] repetitive transcranial magnetic stimulation (rTMS) could attain superior efficacy compared…Anatomical and electrical field determinants of axial motor outcome after bilateral GPi-DBS in Parkinson’s disease
Objective: To determine anatomical and electrical field parameters associated with short-term improvement in axial motor scores after bilateral GPi-DBS in PD. Background: Axial symptoms in…A Large-Scale Digital Parkinson Disease Platform Matches Clinician Identification of Dyskinesia and Uncovers Unmet Need Between Visits
Objective: To evaluate whether continuous remote monitoring can identify dyskinesia at scale, detect between-visit worsening, and support more efficient patient-clinician communication about management. Background: Dyskinesia…Dyskinesia-Hyperpyrexia Syndrome Mimicking a Generalized Seizure in Parkinson’s Disease
Objective: To report a rare case of DHS that was initially misdiagnosed as generalized seizures. Background: Parkinson’s disease (PD) is a progressive neurodegenerative disorder with…Fracture Burden and Health-Related Quality of Life in Older Adults with Parkinson’s Disease in Rural India: A Community-Based Study
Objective: This study aimed to examine the relationship between fracture history and health-related quality of life (HRQoL) among elderly individuals with Parkinson’s disease residing in…Comparison Of Levodopa Dose Frequency And Parkinson’s Kinetigraph Metrics For Screening Advanced Parkinson’s Disease
Objective: 1. Evaluate how well levodopa dose frequency and Parkinson's Kinetigraph (PKG) metrics correspond with the 5-2-1 criteria for identifying Advanced Parkinson Disease (APD)2. Determine…Agreement Between Patient-Reported Experiences of Daily Living and Clinician-Rated Motor Exam Severity in Parkinson’s Disease
Objective: To assess concordance between patient-reported experiences of daily living and clinician-rated motor exam severity in Parkinson’s disease (PD). Background: Clinicians rate PD motor severity…Longitudinal motor network responses to pallidal DBS in cervical dystonia: an ongoing DBS-fMRI study
Objective: This longitudinal MRI study in cervical dystonia uses functional MRI (fMRI) to evaluate neural mechanisms underlying clinical response to deep brain stimulation (DBS), with…
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