Indirect comparison of tolerability of deutetrabenazine and tetrabenazine in the FIRST-HD and TETRA-HD trials
Objective: To compare the tolerability of deutetrabenazine (DTB) and tetrabenazine (TBZ) as observed in the FIRST-HD (NCT01795859) and TETRA-HD (NCT00219804) trials for the treatment of…Temporal course of the UHDRS chorea score in Huntington disease
Objective: To describe the temporal course of Huntington disease (HD) chorea using the total maximal chorea score of the Unified Huntington Disease Rating Scale -…Temporal course of the total motor score in Huntington disease
Objective: To describe the temporal course of motor features in Huntington disease (HD) using the Unified Huntington Disease Rating Scale - Total Motor Score (UHDRS-TMS)…Clinical presentation and genetic characteristics of Huntingtons disease in Croatia: Thirty years of experience
Objective: To report our experience over 30 years with patients with Huntington's disease disease (HD) in Croatia and to assess the presence of oxidative stress…Demographic and phenotypic comparison of Huntington’s disease in Europe and North America: Data from REGISTRY and COHORT, two prospective observational cohort studies
Objective: We tested the assumption that the demographic and clinical spectrum of Huntington's disease (HD) is fairly similar irrespective of the geographical region of origin…Maintenance of balance function in patients with HD treated with deutetrabenazine, as measured by Berg balance test (BBT) in First-HD
Objective: To assess the effect of deutetrabenazine treatment on balance using the BBT in patients with HD in First-HD. Background: Patients with HD have disrupted…Fifteen years of clinical trials in Huntington’s disease: Too many clinical trial failures
Objective: To investigate the trends in Huntington's disease (HD) therapeutic development by analyzing interventional clinical trials publicly registered for the last 15 years. Background: Like…Fast and simple non-invasive screening tool for mitochondrial changes in Huntington’s disease
Objective: To use Complex I and Complex IV Human Protein Quantity Dipstick Assay Kits to analyse mitochondrial changes in buccal epithelial cells of patients with…The assessment of quality of life in patients with early and moderately advanced Huntington disease
Objective: The aim of the study was to determine if available quality of life related scales are useful to detect the deterioration of quality of…Enroll-HD: A global clinical research platform for Huntington’s disease
Objective: To provide an update on the global observational registry study of Huntington's disease (HD) included in Enroll-HD, a platform for HD clinical research. Background:…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.