Predictors of Рostural Instability and Gait Disturbances after STN-DBS in Parkinson’s Disease
Objective: The aim was to identify characteristic pre-surgical visual and vestibular disturbances, as well as neuroimaging changes that could be predictors of PI and gait…Bone Mineral Density in Early Parkinson’s Disease: Correlations with Disease Severity and Prognosis
Objective: This study aimed to evaluate the association between bone mineral density (BMD) and disease severity, progression, freezing of gait (FOG), and fracture risk in…Apathy and Risk of Parkinson’s Disease: A Population-Based Cohort Study
Objective: This study investigated the association between apathy and the risk of incident Parkinson's disease (PD) in community-dwelling adults. Background: Apathy is a core neuropsychiatric…Effect of Aβ on α-synuclein propagation
Objective: To investigate how amyloid-beta (Aβ) pathology affects α-synuclein (α-syn) propagation. Background: Lewy bodies, the pathological hallmark of Parkinson’s disease and dementia with Lewy bodies,…Decreased cholinergic activity in specific brain regions associated with slower lower limb visual choice reaction time in Parkinson’s disease: A [18F]-FEOBV PET study
Objective: To investigate the relationship between cholinergic system changes, as measured by vesicular acetylcholine transporters (VAChT) [18F] fluoroethoxybenzovesamicol ([18F] FEOBV) binding in PET, and cognitive performance, measured as…Utilising Beta Power in Local Networks to Predict Freezing of Gait Events in Parkinson’s Disease
Objective: Our study examined brain network changes during the transition to Freezing of Gait (FOG) versus voluntary stopping. Identifying specific neural alterations may help establish…Spatial Multi-Omics Identifies Early Synaptic Pruning and Context-Specific Dopaminergic Vulnerability in Synucleinopathies
Objective: To investigate the significance of Lewy body pathology (LBP) in relation to midbrain molecular and cellular changes associated with Parkinson's disease (PD). Background: The…Early Impairment in the Immunomodulatory Function of Mesenchymal Stromal Cells Contributes to Heightened Peripheral and Neuroinflammation in Parkinson’s Disease Insights From In Vivo Chronic PD Rat Model and In Vitro PD iPSC Model
Objective: To assess the timeline dependent changes in endogenous Bone-Marrow-Mesenchymal-Stromal-Cells (BMMSC) in in-vivo chronic PD model and validating these cellular modifications in human iPSC derived…Moyamoya Disease and the Risk of Parkinson’s Disease
Objective: We aimed to determine whether the risk of Parkinson’s disease (PD) is increased in patients with Moyamoya disease (MMD) and to identify the potential…Advancing MDS Guidelines for Electronic Clinical Outcome Assessments: Best Practices for Validation and Implementation
Objective: To update and formalize the International Parkinson and Movement Disorder Society (MDS) Clinical Outcomes Assessment Program guidelines on validating and evaluating electronic clinical outcome…
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