Does PET Imaging Modality Influence Artificial Intelligence Performance in Diagnosing Parkinson’s Disease? Diagnostic Test Accuracy Meta-analysis
Objective: To determine whether AI diagnostic performance for Parkinson’s disease differs across PET imaging platforms Background: PET-based artificial intelligence (AI) has emerged as a promising…Neuromelanin Loss Is Associated with Increased Substantia Nigra Free-Water: a Longitudinal Study of Controls, RBD, and PD
Objective: To longitudinally characterize substantia nigra (SN) neuromelanin (NM) and free-water (FW) MRI biomarkers by comparing control, REM sleep behaviour disorder (RBD), and Parkinson’s disease…Large Language Models for Clinical Feature Suggestion from Parkinson’s Disease Clinical Notes
Objective: To generate a list of clinical features representative of Parkinson’s disease from unstructured clinical notes and to evaluate the performance of different large language…DCN-PPN Pathway Activation Improves Motor Dysfunction via Synaptic Plasticity in Parkinson’s Disease
Objective: To define the anatomical and functional connectivity of the DCN-PPN pathway, determine its alterations in PD, and investigate whether impaired synaptic plasticity in this…The “Sequestration” hypothesis: Longitudinal systemic priming and CNS infiltration of Neutrophil Extracellular Traps in Parkinson’s Disease
Objective: To evaluate the longitudinal systemic transcriptomic profile of neutrophil-related pathways and the pathological infiltration of neutrophil extracellular traps (NETs) into the central nervous system…Developing a Unified Advanced Neuromodulation Clinical Pathway for MR-Guided Focused Ultrasound and Deep Brain Stimulation
Objective: To analyze determinants of neuromodulation treatment selection, including patient preferences and clinical eligibility, in a large real-word cohort of patients diagnosed with Parkinson’s Disease (PD) and Essential…Data-driven Longitudinal Trajectories of Hippocampal Volume in Parkinson’s Disease and Across the Neurodegenerative Disease Spectrum
Objective: To elucidate hippocampal (HP) volume trajectories in Parkinson disease (PD) and across the neurodegenerative disease (NDD) spectrum. Background: HP volume is a critical neuroimaging…Disease-Modifying Outcomes Following High Intensity Boxing and Sensory Exercise in Parkinson’s Disease: Results From a Double-blinded Randomized Controlled Trial
Objective: The purpose of this study was to determine whether high-intensity exercise (boxing) and sensory exercise (PD SAFEx™) produce disease-modifying effects on motor symptoms following…Human Snca Knock-In Mouse as a Model for Synucleinopathy Research
Objective: Inter-species differences between mouse and human α-synuclein (asyn) may influence aggregation and pathology in animal models, highlighting the need for models expressing human asyn.…Ion Channel Modulation by Dopamine Receptors in Subthalamic Nucleus Neurons: Implications for Parkinson’s Disease Pathophysiology
Objective: Recent neurophysiological studies indicate that dopamine D2 receptors (D2R) may interact with N-type calcium channels in neurons of the subthalamic nucleus (STN), potentially altering…
- « Previous Page
- 1
- …
- 179
- 180
- 181
- 182
- 183
- …
- 1942
- Next Page »