The N6-Methyladenosine mRNA Methylase METTL14 Regulates TLR4-mediated intestinal dysfunction in Parkinson’s Disease
Objective: The aim of this study is to explore the function and mechanism of RNA m6A modification in gut-derived inflammation of Parkinson's disease (PD). Background:…Association between subjective and objective language measures in DBS candidates
Objective: Determine if expressive language measures from neuropsychological testing correspond to subjective communication struggles in Deep Brain Stimulation (DBS) candidates. Background: A number of studies…Novel modifiers of heterozygous pathogenic Parkin variant penetrance in Parkinson’s disease
Objective: To identify novel genes and pathways acting as modifiers of pathogenic Parkin variant (PV) penetrance in affected compared to unaffected carriers of heterozygous Parkin PVs…Effects of cerebellar cTBS on motor symptoms in Huntington’s disease: a feasibility and pilot study
Objective: To evaluate the feasibility and preliminary clinical effects of a single session of cerebellar cTBS in patients with Huntington's disease (HD) with mild-moderate motor…Diffuse cerebellar edema in acute anti-Yo positive paraneoplastic cerebellar degeneration: A case report
Objective: To report a case of acute anti-Yo positive paraneoplastic cerebellar degeneration (PCD) with atypical brain MRI findings. Background: PCD is a rare disease but…PD.ai – Detection of Parkinson’s Disease with gait-based biomarkers using AI techniques
Objective: This study evaluated the utility of Artificial Intelligence (AI) in detection of patients with Parkinson’s disease from stride dynamics. Background: Parkinson’s Disease (PD) is…Parkinsonism in sjogren disease
Objective: explain the cause of parkinsonism in Sjogren's syndrome Background: Sjogren's syndrome (SS) may be associated with various pathologies of the central nervous system. It…Sympathetic tone abnormalities in subjects at risk for Parkinson’s Disease without evidence of nigrostriatal neurodegeneration: a multimodal biomarker study
Objective: To study autonomic dysfunction in subjects with idiopathic REM sleep behavior disorder (iRBD) and at least one pre-motor symptom of Parkinson's disease (PD). Background:…Visuo-spatial processing is linked to cortical glutamate dynamics in Parkinson’s disease – a 7 Tesla functional MRS study
Objective: To investigate alterations of glutamate metabolism in the occipital cortex during visual processing in patients with Parkinson’s disease (PD). Background: Cognitive decline is a…A novel, population-specific PINK1 p.F385S loss of function mutation in an Indian family with Parkinson’s disease
Objective: To understand the molecular function of a novel missense PINK1 variant identified in an Indian family with Parkinson’s disease (PD). Background: The molecular understanding…
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