miRNAs from blood serum as an early diagnostic biomarker for Parkinson’s disease: A study in an animal model
Objective: This work aims to elucidate miRNA-based biomarkers for the early stages of Parkinson`s Disease diagnosis in a chemically induced PD rat model. Background: The…Correlation between fatigue, sleep dysfunction and health-related quality of life in Parkinson’s disease patients
Objective: To determine the correlation between fatigue, sleep dysfunction and health-related quality of life in Parkinson’s disease (PD) patients. Background: Fatigue and sleep dysfunction are…Regional Atrophy and Motor Speech in PSP
Objective: This study examined the association of regional atrophy on MRI and motor speech in PSP. Background: Motor speech impairment is common in PSP[1]. Although…Neuropalliative communication curriculum: A review of the literature and needs assessment
Objective: We aim to improve neuropalliative education in neurology trainees by creating a reproducible didactic curriculum targeting specific communication techniques using case-based sensitive scenarios commonly…Tardive dystonia manifesting in lid-opening apraxia, oromandibular dystonia, and laterocollis after long-term sulpiride use
Objective: We describe a patient who developed tardive dystonia after sulpiride treatment for over two decades. Few cases have been reported[1-3], thus we offer an…Data-driven subtypes of multiple system atrophy and the implication on prognosis
Objective: To determine the clinical subtypes of MSA using data-driven approach and to compare the differences of the subtypes on survival and bed-ridden rates. Background:…Pilot study of outpatient rehabilitation of patients with Huntington’s disease in Russia
Objective: The benefits of exercises and physical activity in Huntington's disease in terms of motor function, gait speed, and balance, as well as a range…Cost-effectiveness of Lee Silverman Voice Treatment LOUD (LSVT®) versus NHS Speech and Language Therapy versus control for dysarthria in Parkinson’s disease: An economic evaluation alongside the PD COMM trial
Objective: We evaluated the cost effectiveness of two speech and language therapy techniques compared with no therapy in people with Parkinson's disease who have problems…Altered nucleus accumbens functional connectivity precedes apathy in Parkinson’s disease
Objective: To investigate whether changes in connectivity between neural regions that are associated with goal-directed behaviour predict future development of apathy in people with Parkinson’s…Long-term effects of a mobile technology-based brisk walking program on Parkinsonian symptoms in Parkinson’s disease – a randomized controlled trial
Objective: To evaluate the effectiveness of a 6-month mobile technology-based brisk walking program on motor and non-motor symptoms and self-perceived ability in people with Parkinson’s…
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