Ocular microtremor in Parkinson’s Disease: Protocol for an observational pilot study
Objective: This study aims to examine OMT in people with PD (PwPD) compared to healthy older adults. Identifying OMT as a PD biomarker could better…Heart-rate variability as a new marker for freezing predisposition in Parkinson’s disease
Objective: We aim to investigate for the first time whether it is possible to detect a predisposition for upcoming Freezing of Gait (FoG) events from…Speech, gait and vestibular instrumental assessment in CANVAS: a case series.
Objective: To describe through a systematic clinical-instrumental approach speech, gait and vestibular alterations in cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS). Background: CANVAS…Patterns of Parkinson disease mitochondrial brain function indexed by 31P magnetic resonance spectroscopy
Objective: To examine whether individuals with PD show greater temporal than frontal high energy phosphate metabolism (31P MRS ATP) that is similar or different from…Differences in gray matter atrophy and functional connectivity between motor subtypes of Parkinson’s disease
Objective: This study compared gray matter volume (GMV) and functional connectivity among patients with Parkinson’s disease involving postural instability/gait difficulty (PD-PIGD), patients with tremor-dominant Parkinson’s disease (PD-TD) and healthy…Localisation of distinct brain networks in premanifest and manifest Huntington’s disease
Objective: To map the brain networks underlying Huntington’s Disease (HD), testing whether there are distinct networks involved in premanifest and manifest disease stages. Background: HD…Distinct temporal and spatial alteration of immunoproteasome in Parkinson’s Disease pathogenesis
Objective: We aimed to investigate the temporal and spatial evolution of immunoproteasome in the central nervous system (CNS) during PD pathogenesis using mouse model. Background:…People with Parkinson’s Disease present compensatory cortical activity patterns during split-belt treadmill walking, regardless of leg or disease side dominance.
Objective: To study the effects of Parkinson’s Disease (PD) on cortical activity during split-belt (SB) walking compared to tied-belt (TB) walking, and the impact of…White matter hyperintensities associated with impulse control disorders in Parkinson’s disease
Objective: Given the limited number of non-motor features studied in this context, our aim was to reveal the potential association between the severity of white…Brain-behavior quantification and synchronization to drive closed-loop deep brain stimulation
Objective: Closed-loop DBS systems require a neural biomarker to responsively turn on stimulation, which in turn requires neurophysiological quantification synchronized to behavior or symptoms. Our…
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