Subject-specific investigation of pathways underlying therapeutic outcomes of deep brain stimulation for Essential Tremor
Objective: To relate subject-specific pathway activation models of motor thalamic deep brain stimulation (DBS) to clinical outcomes in patients with Essential Tremor (ET). Background: Computational…Yet another cause of Corticobasal Syndrome: A case of TREM2 related Alzheimer’s Disease presenting as Corticobasal Syndrome
Objective: We present a case of corticobasal syndrome associated with a variant in the gene triggering receptor expressed on myeloid cells 2 (TREM2) and present…Pathological neuronal Oscillations in an animal model of Rapid-Onset Dystonia-Parkinsonism
Objective: The aim of our study was to investigate neuronal network activity in the basal ganglia (BG) and cerebellum (CB) in Rapid-Onset Dystonia-Parkinsonism (RDP). Background:…10 year longitudinal change in clinical and biological characteristics of sporadic Parkinson Disease PPMI cohort
Objective: To present data on 10 year longitudinal clinical and biological characteristics of sporadic Parkinson Disease (sPD) participants in the Parkinson’s Progression Markers Initiative (PPMI)…Hereditary spastic paraplegia type 4 (SPG4): an international multicenter clinical and genetic study
Objective: To describe the epidemiological, clinical, and genetic features of patients affected by hereditary spastic paraplegia (HSP) in an international cohort of affected individuals.To describe…Understanding neuropsychological features of dopa responsive dystonia in children
Objective: To describe the neuropsychological features in five siblings with dopa responsive dystonia (DRD) due to autosomal dominant GCH1 related disease (AD GCH1). Background: Although…Impact of dual tasking and sensory manipulation on balance in Fragile X-associated tremor/ataxia syndrome (FXTAS) and potential prodromal postural sway deficits in asymptomatic FMR1 premutation carriers
Objective: To detect subtle postural sway deficits in FMR1 premutation carriers who are asymptomatic for signs of FXTAS and determine the impact of dual tasking…Application of multi-parametric diffusion MRI in detecting visual disturbances in advanced Parkinson’s disease population
Objective: We aimed to identify differences in multi-parametric diffusion indices (DTI, NODDI, and DKI) between Parkinson’s disease patients with visual disturbances and those without. Background:…An Analysis of Subgroups of Multiple System Atrophy Patients from Ampreloxetine Phase 3 Trials
Objective: To present results in the subset of patients with multiple system atrophy (MSA) and relevant MSA subgroups from two ampreloxetine phase 3 trials for…Zonisamide in advanced Parkinson’s disease: a randomized placebo-controlled study in Egyptian population
Objective: To investigate safety and efficacy of ZNS on motor ,non motor symptons and quality of life in advanced PD in egyptian populatiin Background: Zonisamide…
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