Quantitative gait analysis to evaluate changes in gait pattern after Botulinum toxin A injection by hemiparesis
Objective: This retrospective study aimed to assess the effect of Botulinum toxin A (BoNT-A) injections in the lower limbs of hemiparetic patients on gait parameters,…Stability of beta oscillations during aDBS in Parkinson’s disease: a methodology for reliable assessment
Objective: In this work, we describe a methodology to assess whether a specific oscillation, considered as biomarker for adaptive DBS (aDBS), is stabilized during stimulation,…Late onset cerebellar ataxia in patients treated with VIM DBS
Objective: To highlight the predictors for onset of cerebellar ataxia in patients treated with deep brain stimulation (DBS) of the Thalamic Ventral Intermediate Nucleus (VIM)…Parkinson’s Disease Hospital Optimization Project
Objective: To describe The Parkinson’s Disease Hospital Optimization Project (PD-HOP) that we established to optimize inpatient care and improve the hospital experience and outcomes for…Alterations of gait as an early marker of incipient alpha-synucleinopathy
Objective: To investigate early motor signs of α-synucleinopathies in patients with isolated REM sleep behavior disorder (iRBD) using gait analysis. Background: iRBD is an early…RNA editing contributes to the inflammatory astrocytic response in Parkinson’s disease.
Objective: 1) Using an IPSC derived cell model to explore astrocytic responses alone and cocultured neurons to alpha-synuclein oligomer (αsynO) treatment.2) Determine the extent to…Exome sequencing of 584 Chinese proband with brain calcification
Objective: The aim of this study is to evaluate the diagnostic value of whole exome sequencing in Chinese patients with brain calcification, and to provide exome sequencing-based insights into the genetic…Anodal Transcranial Direct Current Stimulation (tDCS) on sensorimotor cortex in patients with early-onset Parkinson’s Disease: a Pilot Study.
Objective: To evaluate the clinical effects of anodal Transcranial Direct Current Stimulation (tDCS) application on sensorimotor cortex in a group of early-onset Parkinson’s Disease patients.…Case Study: Pitfalls of Commercial Genetic Testing for Huntington’s Disease
Objective: We present a family with initial false negative commercial testing for Huntington Disease (HD) and subsequent whole genome sequencing (WGS) that revealed an expanded…Mitochondrial DNA copy number is associated with the severity of motor symptoms and dementia in Parkinson’s disease
Objective: We aimed to investigate the diagnostic and prognostic role of blood mitochondrial DNA copy number (mtDNA-CN) measured by whole genome sequencing (WGS) in relation…
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