Characterization of neuromelanin MRI as a potential Parkinson’s Disease biomarker in a multi-site longitudinal study
Objective: To investigate (1)longitudinal change and (2)cross-sectional vendor differences in neuromelanin MRI in substantia nigra pars compacta(SNpc) in PD patients. Background: Neuromelanin(NM) MRI is a…Neuroanatomical underpinnings of apathy in Parkinson’s Disease
Objective: To investigated the integrity of white matter tracts within basal ganglia-frontal networks in PD patients with and without apathy, and relate these to specific…A Narrative Review of Literature on Exercise Therapy and Cognitive Impairment in Individuals with Parkinson’s Disease: The Role of Epigenetics as a Mediator.
Objective: This narrative review explored the potential role of exercise as an epigenetic mediator of cognitive function in people with PD and the possible underlying…Trends in incidence of hospitalizations in Parkinson´s Disease in Spain (2010-2019)
Objective: To estimate the incidence of in-hospital admissions of Parkinson´s disease (PD) in Spain during the last decade (2010-2019) and describe the epidemiology of these…Inflammatory changes in subjects with de novo Parkinson’s disease
Objective: To examine whether inflammation is present in subjects newly diagnosed with Parkinson’s disease (PD). Background: Evidence for the role of inflammation in PD has…IncobotulinumtoxinA to treat sialorrhea in Parkinson’s disease: a real-life study
Objective: We evaluate the long-term efficacy and safety of incobotulinumtoxinA injections in advanced Parkinson’s disease (PD) patients suffering from sialorrhea (10 injection cycles (IC) into…Safety and tolerability of Nilotinib in patients with Huntington’s disease
Objective: To investigate the safety and tolerability of nilotinib, an FDA-approved drug for leukemia, in individuals with Huntington’s disease (HD). Background: Previous clinical studies in…Comorbidities in Huntington’s disease: An Enroll-HD analysis
Objective: Determine the frequency of comorbidities in people with Huntington’s disease (PwHD) in comparison to non-carrier controls in the Enroll-HD cohort. Background: Despite some publications…Diagnostic Utility of I123-FP-CIT Single Photon Emission Computed Tomography for Patients with Clinically Uncertain Parkinsonian Syndrome
Objective: This study investigated the impact of I123-FP-CIT single photon emission computed tomography (SPECT) for the diagnosis of patients with clinically uncertain parkinsonian syndrome (CUPS)…Non-dopaminergic system is related with motor reserve in Parkinson’s disease
Objective: To find related brain structures with the motor reserve in Parkinson's disease (PD). Background: There is a discrepancy between the severity of parkinsonism and dopaminergic…
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