12-week Aerobic Interval Training Induces Hemisphere-Specific Neuroprotection in Parkinson’s Disease: A Multimodal MRI, [18F]Fluorodopa PET/CT and BDNF Study
Objective: To investigate whether a 12-week aerobic interval training (AIT) can preserve subcortical brain structures in early Parkinson’s disease (PD) and whether these effects are…Electrophysiological Tremor Analysis In Tremor-Dominant And Postural Instability And Gait Difficulty Phenotypes Of Parkinson’s Disease
Objective: To define the differences in characteristics on electrophysiological tremor analysis between the tremor-dominant (TD) and Postural Instability and Gait Difficulty (PIGD) phenotype. Background: Based…Global Parkinson´s Symptoms Index Correlates with Changes in Quality of Life and Autonomy for Activities of Daily Living
Objective: The aim of the present study was to know if a global assessment of Parkinson's disease (PD) using a new proposed index correlated with…Acupuncture Combined with Anti-Parkinson Medication Improves Objective Balance Parameters in Patients with Parkinson’s Disease
Objective: To evaluate whether acupuncture combined with anti-Parkinson medication improves balance in patients with PD. Background: Parkinson's disease (PD) frequently causes balance dysfunction in older patients.…Long-term safety of deep brain stimulation (DBS): Real-world evidence
Objective: In this analysis, we aimed to evaluate long-term safety of DBS systems in real-world use. Background: Deep brain stimulation (DBS) is an established therapy for…Atypical vascular parkinsonism from a midbrain lesion with excellent dopaminergic response
Objective: To present a patient with parkinsonism resulting from an ischemic lesion in the midbrain that exhibited a favorable response to dopaminergic therapy, with anatomical…The Emerging Landscape of Genotype-Stratified Clinical Trials in Parkinson’s Disease and Atypical Parkinsonian Disorders
Objective: To characterize the landscape of genotype-stratified clinical trials in Parkinson’s disease (PD) and atypical parkinsonian disorders (APD), including therapeutic targets, geographic representation, and trial…PPP2R2B Splice Variant Dysregulation Promotes Mitochondrial Association and Neuronal Apoptosis in iPSC-Derived Neurons from Spinocerebellar Ataxia Type 12 Patient
Objective: This study aimed to investigate the impact of PPP2R2B mutation in Spinocerebellar Ataxia Type 12 (SCA12) by analysing PPP2R2B splice variant expression, subcellular localization,…Intravenous AAVrh.10hFXN (LX2006) Gene Therapy in Friedreich Ataxia: Early Neurologic Assessment from Two Phase 1 and 2 Studies
Objective: To evaluate neurologic measures of efficacy of intravenous AAVrh.10hFXN (LX2006) gene therapy in adults with Friedreich ataxia, based on data from the SUNRISE-FA study…Multimodal Deep Learning for Parkinson’s Disease Screening: Fusing Quantitative Gait Analysis and Clinical Features
Objective: To develop and validate a machine learning model integrating quantitative gait parameters and clinical features to enhance the diagnostic accuracy of Parkinson's disease (PD)…
- « Previous Page
- 1
- …
- 59
- 60
- 61
- 62
- 63
- …
- 1942
- Next Page »