Multimodal Deep Learning for Parkinson’s Disease Screening: Fusing Quantitative Gait Analysis and Clinical Features
Objective: To develop and validate a machine learning model integrating quantitative gait parameters and clinical features to enhance the diagnostic accuracy of Parkinson's disease (PD)…Icariin, a Flavonoid from Epimedium, Confers Dopaminergic Neuroprotection and Neuromodulation in MPTP-Induced Parkinsonian Rats
Objective: The present study aims to evaluate the neuroprotective and neuromodulatory properties of icariin in an MPTP-induced Parkinsonian rat model. Background: Parkinson Disease (PD) is…Urine and Plasma Bis(monoacylglycero)phosphate (BMP) in Asian LRRK2 p.G2385R and p.R1628P Variant Carriers with Parkinson’s Disease
Objective: To compare urine and plasma bis(monoacylglycero)phosphate (BMP) levels in Parkinson disease (PD) patients carrying Asian-prevalent LRRK2 variants (p.G2385R, p.R1628P) against idiopathic PD (iPD) and…Clinical Utility of DaT-SPECT as a Predictive Tool for the Development of Parkinson’s Disease and Related ɑ-synucleinopathies in REM-Behavior Disorder
Objective: The aim of this systematic review was to analyze the available literature and evaluate the efficacy of DaT-SPECT for the prediction of PD phenoconversion…Prospective International Registry Evaluating Real-World Clinical and Quality-of-Life Outcomes of Directional Deep Brain Stimulation in Essential Tremor
Objective: To assess real-world clinical effectiveness and patient-reported outcomes associated with a multiple independent constant current (MICC) directional deep brain stimulation (DBS) system in individuals…Preservation of Cognition Following Intravenous Mesenchymal Stem Cell Therapy in Parkinson’s Disease: Secondary Analysis of a Randomized Trial
Objective: To evaluate longitudinal changes in global cognition following intravenous allogeneic bone marrow–derived mesenchymal stem cell (allo-hBM-MSC) therapy in Parkinson’s disease (PD). Background: Cognitive impairment…Central Autonomic Network Alterations in MSA: From Subcortical Degeneration to Prefrontal Reorganization
Objective: To characterize disease- and symptom-specific alterations in the central autonomic network (CAN) in multiple system atrophy (MSA) and associations with autonomic dysfunction. Background: Autonomic…Prognostic Impact of GBA Variants on Mortality in Parkinson’s Disease: A Systematic Review and Meta-Analysis
Objective: This systematic review and meta-analyses aim to synthesize longitudinal evidence of GBA variants as a prognostic factor for all-cause mortality in Parkinson’s disease (PD).…Baseline plasma neurofilament light and phosphorylated tau 181 levels predict longitudinal cognitive decline in APOE4 and long SNCA Rep1 carriers in Parkinson’s disease
Objective: Plasma neurofilament light (NfL; a marker of axonal injury) and phosphorylated tau 181 (pTau181) are biomarkers that have been associated with cognitive decline in…Longitudinal Decline of Alanine Aminotransferase Activity in Parkinson’s Disease and Its Association with Disease Duration
Objective: To characterize longitudinal trajectories of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activity and the neutrophil-to-lymphocyte ratio (NLR) in Parkinson’s disease (PD) and healthy…
- « Previous Page
- 1
- …
- 58
- 59
- 60
- 61
- 62
- …
- 1942
- Next Page »