Long-term safety of continuous levodopa/carbidopa infusion with ND0612: Data from patients who continued past one year in the BeyoND study
Objective: To report long-term safety and tolerability data from the ongoing BeyoND study (NCT02726386) for patients who continued treatment past the one-year primary endpoint. Background:…Plasma p-Tau181 and p-Tau231 in Parkinson’s Disease
Objective: To explore whether plasma phosphorylated tau (p-Tau) 181 and p-Tau231 levels are associated with cognition in a Parkinson’s Disease (PD) cohort. Background: We recently…A facilitated self-management toolkit for people with Parkinson’s disease: A feasibility study of ‘Live Well with Parkinson’s
Objective: To assess the feasibility and acceptability of a theory and evidence-based digital facilitated self-management toolkit for people with Parkinson’s: ‘Live Well with Parkinson’s’. Background:…Inflammatory microglial and astroglial phenotype associated with pathological alpha-synuclein inclusions in the substantia nigra
Objective: To characterize neuroinflammatory gene expression in microglia and astrocytes associated with early alpha-synuclein (a-syn) inclusion formation. Background: Parkinson’s disease (PD) is characterized by alpha-synuclein…Isolated craniocervical dystonia without neuropsychiatric manifestations associated with NMDA-receptor antibodies
Objective: N-methyl-D-aspartate receptor (NMDAR) encephalitis classically spans neuropsychiatric disturbance, autonomic dysfunction and salient movement disorders. Attenuated presentations are increasingly recognised; however, presentations with an isolated…Alterations in neuron-derived exosomal cargo in Parkinson Disease
Objective: The main objectives are 1) the confirmation of exosome isolation, based on iPSC-derived midbrain neuron model, 2) the identification of α-synuclein cargo of PD-patient…Effects of directional subthalamic deep brain stimulation on gait and balance in Parkinson Disease patients.
Objective: To assess the effects of directional STN-DBS on gait and balance in PD patients Background: STN-DBS is efficient to treat motor signs in PD…The effects of on-demand auditory cueing on home-based freezing of gait in people with Parkinson’s disease
Objective: To evaluate the effects of on-demand auditory cueing on video-rated freezing of gait (FOG) during home-based FOG-provoking tests in people with Parkinson’s disease. Background:…Influence of dopaminergig medication and subthalamic nucleus deep brain stimulation on impulsive decision making in Parkinson’s disease
Objective: To investigate how impulsive decision making is modulated by regular dopaminergic medication and by switching between active contacts of subthalamic nucleus stimulation Background: Impulsive…Exploring the diversity of alleviating manoeuvres in Cervical Dystonia
Objective: We explored five different categories of alleviating manoeuvres (AMs) in patients with cervical dystonia (CD): pure sensory; sensorimotor manoeuvres in which sensory input is…
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