Exploring the diversity of alleviating manoeuvres in Cervical Dystonia
Objective: We explored five different categories of alleviating manoeuvres (AMs) in patients with cervical dystonia (CD): pure sensory; sensorimotor manoeuvres in which sensory input is…Impact of DBS on cognitive functions in Parkinson’s disease in 1 year follow-up
Objective: The aim of our study was to compare performance in neuropsychology tests in patients with Parkinson’s disease (PD) with implanted electrodes of Deep Brain…Blood-derived α-synuclein from Parkinson´s disease patients is able to seed pathology
Objective: To identify seeding capacities of soluble α-synuclein (α-syn) conformers derived from neuronal extracellular vesicles (NEs) from Parkinson´s disease (PD) patients. Background: PD pathology is…A trail towards understanding cognitive impairment in PSP
Objective: To investigate cognitive impairment in 22 patients with Progressive Supranuclear Palsy with Richardson syndrome (PSP-RS). Background: PSP is a neurodegenerative disease and common differential…What if it is not a Functional Movement Disorder?
Objective: To describe a consecutive cohort of patients with non-functional neurological diseases that were initially diagnosed as Functional Movement Disorders (FMD). Background: Functional and non-Functional…Dopamine-independent cortical disinhibition in Parkinson’s disease
Objective: To test the hypothesis that cortical disinhibition in Parkinson's disease is a dopamine-independent process. Background: Motor cortex alterations in Parkinson's disease are classically considered…Second Project: The feasibility and efficacy of virtual visits compared to in-person visits for management of Parkinson’s disease. A pilot, international, longitudinal, multicenter trial (NCT04695353).
Objective: To investigate the feasibility and efficacy of virtual visits for Parkinson's Disease (PD) compared to in-person visits. Background: Considering the limited access to specialists…Diffusion-weighted imaging based free-water investigation in Parkinsonian disorders
Objective: To investigate free-water (FW) changes in Parkinson's disease (PD), Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Background: Various parkinsonian syndrome includes PD,…Validation of fully automated tremor analysis on common videos based on Computer Vision.
Objective: This project aims towards the development and validation of a fully automated framework for tremor analysis using common video recordings. Background: Till date, sensor-based…Impact of istradefylline on the adjustment of levodopa dose escalation in Parkinson’s disease: Results of the ISTRA ADJUST PD randomized, controlled study
Objective: To evaluate the effect of istradefylline (IST), an adenosine A2A receptor antagonist, on the adjustment of levodopa dose escalation in patients with Parkinson’s disease…
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