High prevalence of REM sleep behavior disorder (RBD) in advanced, fluctuating Parkinson’s disease (PD) patients: comparison of clinical parameters between PD patients with and without RBD
Objective: The aim of this study was to investigate the prevalence of RBD in advanced PD patients and to compare the clinical characteristics of advanced…China’s Jidong Restless Legs Syndrome Cohort Study: Objectives, Design, and Baseline Screening
Objective: The authors supposed, restless legs syndrome . partly results from cardiovascular and cerebrovascular disease, and further more, results in the sexual functional changes. Background:…SNCA hypomethylation in rapid eye movement sleep behavior disorder is a potential biomarker for Parkinson’s disease
Objective: We aimed to explore whether there were different distributions of α-synuclein at a genetic and/or protein level in patients with iRBD. Background: α-Synuclein has been related to…Identification of Factors that Impact Adherence to OnabotulinumtoxinA Treatment for Spasticity in Post-Stroke and Multiple Sclerosis Patients from ASPIRE
Objective: Identify baseline clinical characteristics and treatment-related factors that impact adherence to onabotulinumtoxinA (onabotA) treatment in post-stroke and multiple sclerosis (MS) patients from the Adult…Cost-Analysis of the Use of IncobotulinumtoxinA and AbobotulinumtoxinA for the Treatment of Post-Stroke Upper Limb Spasticity Based on Recommended Dosing for Muscles and Clinical Patterns
Objective: To carry out a cost-analysis based on the respective recommended dosing per muscle using IncobotulinumtoxinA (INCO) and AbobotulinumtoxinA (ABO) for the treatment of post-stroke…Heterozygous mutation in CCDC88C gene as a cause of early onset pure hereditary spastic paraplegia
Objective: The objective of this study was to identify the molecular diagnosis of a Sudanese lady presenting with pyramidal signs and symptoms using whole exome…Transcutaneous spinal cord current stimulation modulate Reactive Oxygen Species (ROS) in multiple sclerosis patients
Objective: To investigate the effect of Transcutaneous spinal cord current stimulation (tsDCS) on oxidative stress in patients with multiple sclerosis (MS). Background: MS is a…Treatment of Medication-Refectory Holmes Tremor by Simultaneous Thalamic Ventral Intermediate (VIM) Nucleus and Subthalamic Nucleus (STN) Deep Brain Stimulation-A Case Report
Objective: To report a case of medication refractory Holmes tremor in a patient with pontine stroke and multisystem atrophy-cerebellar type (MSA-C) successfully treated with bilateral,…New tool to localize seizure onset zone from sEEG signal-connectivity epileptogenicity index
Objective: The main diagnostic challenge of drug resistant epilepsies is to find epileptogenic zone, which will be enough to remove to reach seizure freedom. These…Acute Medically Refractory Hemichorea-Hemiballismus Treated by Unilateral Pallidotomy: A Case Report
Objective: To describe the case of a 31-year-old man with partially treated cryptococcal meningitis complicated by acute hemiballismus treated with unilateral radiofrequency pallidotomy. Background: Hemiballismus has classically been described as a result of vascular or metabolic insults to…
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