Access to rehabilitation therapy for people with Parkinson’s disease in Rome, Italy
Objective: This survey aimed to evaluate patients’ awareness of healthcare roles, access to care, and use of rehabilitation services in the Rome region, Italy. Background:…Diffusion MRI Evidence of Cerebellar Involvement in Cognitive Dysfunction in Parkinson’s Disease
Objective: To determine whether cerebellar axonal microstructural abnormality is associated with cognitive performance in PD. Background: Cognitive impairment in Parkinson’s disease (PD) often affects executive…Clinical Markers of Monogenic Mimics in Atypical Parkinsonism: Findings From a 150-Patient Series
Objective: We aimed to (1) define the yield and spectrum of genetic findings in an unselected Atypical Parkinsonism (AP) series and (2) identify clinical markers…Increased Pre-Alpha EEG Functional Connectivity Forecasts Future Cognitive Decline in Parkinson’s Disease
Objective: To evaluate whether resting-state EEG functional connectivity (rsEEG-FC) forecasts cognitive decline three years later in Parkinson’s disease (PD). Background: Cognitive performance and trajectories of…Physical Activity is Associated with Attenuated Motor and Cognitive Progression in Parkinson’s Disease
Objective: To determine whether physical activity (PA) modifies the rate of motor and cognitive progression in Parkinson’s disease (PD) and to identify specific components of…Impact of Alpha-Synuclein Burden and Cellular Stress on GBA-PD Macrophage
Objective: This study explores how non-neuronal dysfunction drives the rapid progression of GBA-PD, aiming to identify therapeutic targets that restore protein degradation and cellular stability.…Image-Guided DBS Programming in Dystonia: Experience from a Tertiary Public Brazilian Center
Objective: To illustrate the clinical utility of postoperative DBS lead reconstruction and image-guided programming in genetic dystonia Background: DBS of the globus pallidus internus (GPi)…5-year Longitudinal Changes in Non-motor Symptoms and Their Association With Motor Progression in Parkinson’s Disease
Objective: To examine longitudinal relationships between non-motor symptoms (NMS) and motor progression in Parkinson’s disease (PD), and to determine whether baseline NMS predict motor decline…Investigating the Role of Biallelic EPG5 Variants in Parkinson’s Disease
Objective: Investigate EPG5 role in PD aetiology. Background: Disruption of the lysosome-autophagy pathway is a recurrent feature in Parkinson’s disease (PD). EPG5 bi-allelic loss-of-function variants have been…Non‑Motor Outcomes after STN-FUS for Parkinson’s disease
Objective: To assess changes in non-motor symptoms(NMS) in PD after focused ultrasound subthalamotomy(STN-FUS). Background: NMS impair quality of life in PD.STN-FUS improves motor signs in PD but…
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